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Podcasts

Beyond the Mic: Exploring the Journeys of Leaders.

Cholestatic Pruritus Across the Age Spectrum: What Are You Missing?

When considering cholestatic pruritus across the age spectrum, a key point to remember is that while the underlying mechanism is similar, pediatric patients often present with unique challenges in diagnosis and management due to factors like limited communication abilities, potential side effects of medications, and the need for careful dosage adjustments; additionally, older adults might have co-morbidities that complicate treatment and require a more nuanced approach to managing pruritus

Webcasts

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Hepatitis B and D Infection

Joseph K. Lim, MD
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HBV/HDV Hot Topics & Virtual Roundtable

Dr. Robert Wong & Expert Panelists
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HBV, HCV, and HDV

Vinod Rustgi, MD, MBA & Nikolaos Pyrsopoulos, MD
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Publications

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Diagnosis and Management of Hepatitis Delta Virus Infection

Hepatitis D virus (HDV) depends on hepatitis B virus (HBV) to enter and exit hepatocytes and to replicate. Despite this dependency, HDV can cause severe liver disease. HDV accelerates liver fibrosis, increases the risk of hepatocellular carcinoma, and hastens hepatic decompensation compared to chronic HBV monoinfection. The Chronic Liver Disease Foundation (CLDF) formed an expert panel to publish updated guidelines on the testing, diagnosis, and management of hepatitis delta virus. The panel group performed network data review on the transmission, epidemiology, natural history, and disease sequelae of acute and chronic HDV infection. Based on current available evidence, we provide recommendations for screening, testing, diagnosis, and treatment of hepatitis D infection and review upcoming novel agents that may expand treatment options. The CLDF recommends universal HDV screening for all patients who are Hepatitis B surface antigen-positive. Initial screening should be with an assay to detect antibodies generated against HDV (anti-HDV). Patients who are positive for anti-HDV IgG antibodies should then undergo quantitative HDV RNA testing. We also provide an algorithm that describes CLDF recommendations on the screening, diagnosis, testing, and initial management of Hepatitis D infection.

Abstract Library

Unlocking Boundless Knowledge Through Abstracts

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Evolving insights into viral hepatitis: Advances, evidence, and expert perspectives from the ESCMID Study Group for Viral Hepatitis (ESGVH) - Part 2: hepatitis B, C, and delta.

Săndulescu Oana (O);Matičič Mojca (M);Garcia Federico (F);Blomé Marianne Alanko (MA);Mondelli Mario U (MU);Irving William (W);Zidovec-Lepej Snjezana (S);Widell Anders (A);Şahin Gülşen Özkaya (GÖ); ()

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Ten-Year Follow-Up After 96 Weeks Treatment With Peginterferon Plus Tenofovir in Hepatitis D (HIDIT-II): Improved Clinical Outcome After Combination Therapy.

Yurdaydin Cihan (C);Kahlhöfer Julia (J);Caruntu Florin Alexandru (FA);Yalcin Kendal (K);Gürel Selim (S);Akarca Ulus S (US);Sprinzl Kathrin (K);Bock Hans H (HH);Bockmann Jan-Hendrik (JH);Papatheodoridis George V (GV);Merle Uta (U);Demir Münevver (M);Hardtke Svenja (S);Keskin Onur (O);Idilman Ramazan (R);Cornberg Markus (M);Wedemeyer Heiner (H);Wranke Anika (A)

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From Hyperendemic to Low Endemicity: The Effect of Hepatitis B Vaccination on HBV and HDV Prevalence in the Brazilian Amazon.

Malheiros Andreza Pinheiro (AP);Gomes-Gouvêa Michele Soares (MS);Ribeiro Leidiane Barbosa (LB);Souza Alex Junior Souza de (AJS);Azevedo Raymundo Soares (RS);Brito Dickson Ciro Nascimento de (DCN);Oliveira Candida Maria Abrahão de (CMA);Nunes Heloisa Marceliano (HM);Pinho João Renato Rebello (JRR)