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PBC | Abstract Library |
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The summaries are free for public
use. The Chronic Liver Disease
Foundation will continue to add and
archive summaries of articles deemed
relevant to CLDF by the Board of
Trustees and its Advisors. |
1. | Prognostic scores for ursodeoxycholic acid-treated patients predict graft loss and mortality in recurrent primary biliary cholangitis after liver transplantation |
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J Hepatol. 2024 Oct;81(4):679-689. doi: 10.1016/j.jhep.2024.05.010.Epub 2024 May 29.
Aldo J Montano-Loza 1, Ellina Lytvyak 2, Gideon Hirschfield 3, Bettina E Hansen 4, Maryam Ebadi 2, Thierry Berney 5, Christian Toso 5, Giulia Magini 5, Alejandra Villamil 6, Frederik Nevens 7, Natalie Van den Ende 7, Albert Pares 8, Pablo Ruiz 9, Débora Terrabuio 10, Palak J Trivedi 11, Nadir Abbas 11, Maria Francesca Donato 12, Lei Yu 13, Charles Landis 13, Jérôme Dumortier 14, Jessica Katharine Dyson 15, Adriaan J van der Meer 16, Rozanne de Veer 16, Mark Pedersen 17, Marlyn Mayo 17, Michael P Manns 18, Richard Taubert 19, Theresa Kirchner 19, Luca S Belli 20, Chiara Mazzarelli 20, Guido Stirnimann 21, Annarosa Floreani 22, Nora Cazzagon 22, Francesco Paolo Russo 22, Patrizia Burra 22, Udi Zigmound 23, Inbal Houri 23, Marco Carbone 24, Giacomo Mulinacci 24, Stefano Fagiuoli 25, Daniel Stephan Pratt 26, Alan Bonder 27, Thomas D Schiano 28, Brandy Haydel 28, Ansgar Lohse 29, Christoph Schramm 30, Darius Rüther 29, Stefania Casu 31, Xavier Verhelst 32, Benedetta Terziroli Beretta-Piccoli 33, Mercedes Robles 34, Andrew L Mason 2, Christophe Corpechot 35; Global PBC Study Group
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2. | Predictors of survival in autoimmune liver disease overlap syndromes |
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World J Hepatol. 2024 Sep 27;16(9):1269-1277. doi: 10.4254/wjh.v16.i9.1269.
Dujinthan Jayabalan 1 2, Yi Huang 3, Luis Calzadilla-Bertot 1 3, Malik Janjua 3, Bastiaan de Boer 4, John Joseph 4, Wendy Cheng 5, Simon Hazeldine 6, Briohny W Smith 3, Gerry C MacQuillan 1 3, Michael C Wallace 1 3, George Garas 1 3, Leon A Adams 1 3, Gary P Jeffrey 1 3
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3. | Predictive factors for decompensating events in patients with cirrhosis with primary biliary cholangitis under different lines of therapy |
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Hepatology. 2024 Oct 1;80(4):791-806.doi: 10.1097/HEP.0000000000000826. Epub 2024 Mar 6.
Javier Ampuero 1 2 3 4, Ana Lucena 1, Marina Berenguer 4 5 6, Manuel Hernández-Guerra 7, Esther Molina 8, Judith Gómez-Camarero 9, Carlos Valdivia 4 10, Elena Gómez 11, Marta Casado 12, Carmen Álvarez-Navascuez 13, Francisco Jorquera 4 14, Luisa García-Buey 15, Álvaro Díaz-González 16, Rosa Morillas 4 17 18, Montserrat García-Retortillo 19, Jose M Sousa 1, Indhira Pérez-Medrano 20, Miguel Á Simón 4 21 22, Javier Martínez 4 23, Juan Arenas 24, María Carlota Londoño 4 25, Antonio Olveira 26, Conrado Fernández-Rodríguez 27; ColHai Registry
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7. | COBALT: A Confirmatory Trial of Obeticholic Acid in Primary Biliary Cholangitis With Placebo and External Controls |
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Am J Gastroenterol 2024 Aug 14. doi: 10.14309/ajg.0000000000003029. Online ahead of print.
Kris V Kowdley 1, Gideon M Hirschfield 2, Charles Coombs 3, Elizabeth S Malecha 4, Leona Bessonova 4, Jing Li 4, Nuvan Rathnayaka 5, George Mells 6, David E Jones 7, Palak J Trivedi 8, Bettina E Hansen 9 10 11, Rachel Smith 12, James Wason 7, Shaun Hiu 7, Dorcas N Kareithi 7, Andrew L Mason 13, Christopher L Bowlus 14, Kate Muller 15, Marco Carbone 16, Marina Berenguer 17, Piotr Milkiewicz 18 19, Femi Adekunle 20, Alejandra Villamil 21
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11. | COBALT: A Confirmatory Trial of Obeticholic Acid in Primary Biliary Cholangitis With Placebo and External Controls |
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Am J Gastroenterol 2024 Aug 14. doi: 10.14309/ajg.0000000000003029. Online ahead of print.
Kris V Kowdley 1, Gideon M Hirschfield 2, Charles Coombs 3, Elizabeth S Malecha 4, Leona Bessonova 4, Jing Li 4, Nuvan Rathnayaka 5, George Mells 6, David E Jones 7, Palak J Trivedi 8, Bettina E Hansen 9 10 11, Rachel Smith 12, James Wason 7, Shaun Hiu 7, Dorcas N Kareithi 7, Andrew L Mason 13, Christopher L Bowlus 14, Kate Muller 15, Marco Carbone 16, Marina Berenguer 17, Piotr Milkiewicz 18 19, Femi Adekunle 20, Alejandra Villamil 21
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14. | Epigenetic disease markers in primary sclerosing cholangitis and primary biliary cholangitis-methylomics of cholestatic liver disease |
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Hepatol Commun. 2024 Jul 18;8(8):e0496. doi: 10.1097/HC9.0000000000000496.eCollection 2024 Aug 1.
Brian D Juran 1, Bryan M McCauley 2, Elizabeth J Atkinson 2, Erik M Schlicht 1, Jackie K Bianchi 1, Jason M Vollenweider 3, Hong Ye 3, Nicholas F LaRusso 1, Gregory J Gores 1, Zhifu Sun 4, Konstantinos N Lazaridis 1
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16. | Dynamics of liver stiffenss measurement and clinical course of primary biliary cholangitis |
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ClinGastroenterolHepatol. 2024Jul15:S15423565(24)006323.doi:10.1016/j.cgh.2024.06.035. Online ahead of print.
Laurent Lam 1, Pierre-Antoine Soret 2, Sara Lemoinne 2, Bettina Hansen 3, Gideon Hirschfield 4, Aliya Gulamhusein 4, Aldo J Montano-Loza 5, Ellina Lytvyak 6, Albert Parés 7, Ignasi Olivas 7, Maria-Carlota Londono 7, Sergio Rodríguez-Tajes 7, John E Eaton 8, Karim T Osman 8, Christoph Schramm 9, Marcial Sebode 9, Ansgar W Lohse 9, George Dalekos 10, Nikolaos Gatselis 10, Frederik Nevens 11, Nora Cazzagon 12, Alessandra Zago 12, Francesco Paolo Russo 12, Annarosa Floreani 12, Nadir Abbas 13, Palak Trivedi 14, Douglas Thorburn 15, Francesca Saffioti 15, Laszlo Barkai 15, Davide Roccarina 15, Vicenza Calvaruso 16, Anna Fichera 16, Adèle Delamarre 17, Natalia Sobenko 18, Alejandra Maria Villamil 18, Esli Medina-Morales 19, Alan Bonder 19, Vilas Patwardhan 19, Cristina Rigamonti 20, Marco Carbone 21, Pietro Invernizzi 21, Laura Cristoferi 21, Adriaan van der Meer 22, Rozanne de Veer 22, Ehud Zigmond 23, Eyal Yehezkel 23, Andreas E Kremer 24, Ansgar Deibel 24, Tony Bruns 25, Karsten Große 25, Aaron Wetten 26, Jessica Katharine Dyson 26, David Jones 26, Cynthia Levy 27, Atsushi Tanaka 28, Jérôme Dumortier 29, Georges-Philippe Pageaux 30, Victor de Lédinghen 17, Fabrice Carrat 1, Olivier Chazouilléres 2, Christophe Corpechot 31; Global & ERN Rare-Liver PBC Study Groups
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17. | Comorbidities, mortality and metabolic profile in individuals with primary biliary cholangitis-A Phenome-Wide-Association-Study |
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Liver Int. 2024 Aug;44(8):2038-2053. doi: 10.1111/liv.15945. Epub 2024 Apr 25.
Paul-Henry Koop 1, Constanze Schwenzer 1, Jan Clusmann 1, Mara S Vell 1, Julius Jaeger 1, Wenfang Gui 1, Christian Trautwein 1, Alexander Koch 1, Tony Bruns 1, Carolin V Schneider 1 2, Kai Markus Schneider 1
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19. | Epigenetic disease markers in primary sclerosing cholangitis and primary biliary cholangitis-methylomics of cholestatic liver disease |
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Hepatol Commun. 2024 Jul 18;8(8):e0496. doi: 10.1097/HC9.0000000000000496.eCollection 2024 Aug 1.
Brian D Juran 1, Bryan M McCauley 2, Elizabeth J Atkinson 2, Erik M Schlicht 1, Jackie K Bianchi 1, Jason M Vollenweider 3, Hong Ye 3, Nicholas F LaRusso 1, Gregory J Gores 1, Zhifu Sun 4, Konstantinos N Lazaridis 1
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21. | Type of calcineurin inhibitor and long-term outcomes following liver transplantation in patients with primary biliary cholangitis - an ELTR study |
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JHEP Rep. 2024 Apr 25;6(8):101100. doi: 10.1016/j.jhepr.2024.101100. eCollection 2024 Aug.
Maria C van Hooff 1, Rozanne C de Veer 1, Vincent Karam 2, Rene Adam 3, Pavel Taimr 4, Wojciech G Polak 5, Hasina Pashtoun 1, Sarwa Darwish Murad 1, Christophe Corpechot 6, Darius Mirza 7, Michael Heneghan 8, Peter Lodge 9, Gabriel C Oniscu 10 11, Douglas Thorburn 12, Michael Allison 13, Herold J Metselaar 1, Caroline M den Hoed 1, Adriaan J van der Meer 1; European Liver and Intestine Transplant Association (ELITA)
Collaborators
European Liver and Intestine Transplant Association (ELITA):
Darius Mirza, Michael Heneghan, Peter Lodge, Gabriel Oniscu, Douglas Thorburn, Michael Allison, Johann Pratschke, Derek Manas, William Bennet, Pal-Dag Line, Emir Hot, Krzysztof Zieniewicz, Bo Goran Ericzon, Jiri Fronek, Jurgen L Klempnauer, Allan Rasmussen, Renato Romagnoli, Petr Nemec, Arno Nordin, Andreas Paul, Paolo De Simone, R J Porte, Gabriela Berlakovich, Daniel Cherqui, Jacques Pirenne, Etienne Sokal, Giorgio Rossi, Daniel Candinas, Philippe Bachellier, Oleg Rummo, Karim Boudjema, Anna Mrzljak, Olivier Soubrane, Herold Metselaar, Stefan Schneeberger, Francis Navarro, Thierry Berney, Christophe Duvoux, Michele Colledan, Luciano De Carlis, Olivier Boillot, Jean Hardwigsen, Francois Rene Pruvot, Bertrand Suc, Marco Vivarelli, Pierre Alain Clavien, Hauke Lang, Maciej Kosieradzki, Frederik Berrevoet, Bruno Heyd, Matteo Cescon, Laurence Chiche, Eberhard Kochs, Umberto Baccarani, Olivier Detry, Michael Bartels, Massimo Rossi, Olivier Soubrane, Olivier Scatton, Vasileios Papanikolaou, Ian Alwayn, Peter Schemmer, N Senninger, Christian Ducerf, Fabrizio Di Benedetto, Giuseppe Tisone, Silvio Nadalin, Zoltan Mathe, Marija Ribnikar, Utz Settmacher, Thomas Becker, Nuno Silva, Jorge Daniel, Irinel Popescu, Valerio Lucidi, Wolf O Bechstein, Thomas Decaens, Jean Gugenheim, Salvatore Gruttadauria, Frausto Zamboni, Murat Zeytunlu, Jorg C Kalff, Toomas Vali, Yaman Tokat, Ernst Klar, Eberhard Kochs, Renato Romagnoli, Julius Janek, Murat Kilic, Krum Katzarov, Lutz Fisher, Emmanuel Buc, Marco Castagneto, Tarkan Unek, Lubomir Spassov, Dirk Stippel, Christiane Bruns, Hans Schlitt, Ephrem Salame, Piotr Kalicinski, Koray Acarli
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22. | Dynamics of liver stiffenss measurement and clinical course of primary biliary cholangitis |
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ClinGastroenterolHepatol. 2024Jul15:S15423565(24)006323.doi:10.1016/j.cgh.2024.06.035. Online ahead of print.
Laurent Lam 1, Pierre-Antoine Soret 2, Sara Lemoinne 2, Bettina Hansen 3, Gideon Hirschfield 4, Aliya Gulamhusein 4, Aldo J Montano-Loza 5, Ellina Lytvyak 6, Albert Parés 7, Ignasi Olivas 7, Maria-Carlota Londono 7, Sergio Rodríguez-Tajes 7, John E Eaton 8, Karim T Osman 8, Christoph Schramm 9, Marcial Sebode 9, Ansgar W Lohse 9, George Dalekos 10, Nikolaos Gatselis 10, Frederik Nevens 11, Nora Cazzagon 12, Alessandra Zago 12, Francesco Paolo Russo 12, Annarosa Floreani 12, Nadir Abbas 13, Palak Trivedi 14, Douglas Thorburn 15, Francesca Saffioti 15, Laszlo Barkai 15, Davide Roccarina 15, Vicenza Calvaruso 16, Anna Fichera 16, Adèle Delamarre 17, Natalia Sobenko 18, Alejandra Maria Villamil 18, Esli Medina-Morales 19, Alan Bonder 19, Vilas Patwardhan 19, Cristina Rigamonti 20, Marco Carbone 21, Pietro Invernizzi 21, Laura Cristoferi 21, Adriaan van der Meer 22, Rozanne de Veer 22, Ehud Zigmond 23, Eyal Yehezkel 23, Andreas E Kremer 24, Ansgar Deibel 24, Tony Bruns 25, Karsten Große 25, Aaron Wetten 26, Jessica Katharine Dyson 26, David Jones 26, Cynthia Levy 27, Atsushi Tanaka 28, Jérôme Dumortier 29, Georges-Philippe Pageaux 30,
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23. | Comorbidities, mortality and metabolic profile in individuals with primary biliary cholangitis-A Phenome-Wide-Association-Study |
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Liver Int. 2024 Aug;44(8):2038-2053. doi: 10.1111/liv.15945. Epub 2024 Apr 25.
Paul-Henry Koop 1, Constanze Schwenzer 1, Jan Clusmann 1, Mara S Vell 1, Julius Jaeger 1, Wenfang Gui 1, Christian Trautwein 1, Alexander Koch 1, Tony Bruns 1, Carolin V Schneider 1 2, Kai Markus Schneider 1
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27. | Patients with autoimmune liver disease have glucose disturbances that mechanistically differ from steatotic liver disease |
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AmJPhysiolGastrointestLiverPhysiol. 2024Jun1;326(6):G736G746.doi:10.1152/ajpgi.00047.2024. Epub 2024 Apr 16.
Anne-Sofie H Jensen 1 2 3, Henriette Ytting 1 4, Mikkel P Werge 1, Elias B Rashu 1, Liv E Hetland 1, Mira Thing 1, Puria Nabilou 1, Johan Burisch 1 4, Kirstine N Bojsen-Møller 4 5, Anders E Junker 1, Lise Hobolth 1, Christian Mortensen 1, Flemming Tofteng 1, Flemming Bendtsen 1 4, Søren Møller 4 6, Mogens Vyberg 7 8, Reza R Serizawa 7, Lise L Gluud 1 4, Nicolai J Wewer Albrechtsen 2 3
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28. | Development and validation of a scoring system to predict response to obeticholic acid in primary biliary cholangitis |
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ClinGastroenterolHepatol. 2024May21:S15423565(24)004828.doi:10.1016/j.cgh.2024.05.008. Online ahead of print.
Antonio De Vincentis 1, Javier Ampuero 2, Francesca Terracciani 3, Daphne D'Amato 4, Alessio Gerussi 5, Laura Cristoferi 5, Nora Cazzagon 6, Emanuela Bonaiuto 6, Annarosa Floreani 6, Vincenza Calvaruso 7, Luca Cadamuro 7, Elisabetta Degasperi 8, Anna Morgando 4, Ester Vanni 4, Ana Lleo 9, Francesca Colapietro 9, Domenico Alvaro 10, Antonino Castellaneta 11, Sara Labanca 12, Mauro Viganò 13, Marco Distefano 14, Valeria Pace Palitti 15, Chiara Ricci 16, Nicoletta De Matthaeis 17, Marco Marzioni 18, Elena Gómez-Dominguez 19, Jose-Luis Montero 20, Esther Molina 21, Luisa Garcia-Buey 22, Marta Casado 23, Marina Berenguer 24, Isabel Conde 24, Miguel-Angel Simon 25, Javier Fuentes 26, Pedro Costa-Moreira 27, Guilherme Macedo 27, Francisco Jorquera 28, Rosa-Maria Morillas 29, Jose Presa 30, Jose-Manuel Sousa 2, Dario Gomes 31, Luis Santos 31, Antonio Olveira 32, Manuel Hernandez-Guerra 33, Leire Aburruza 34, Arsenio Santos 35, Armando Carvalho 35, Juan Uriz 36, Maria-Luisa Gutierrez 37, Elia Perez 37, Luchino Chessa 38, Adriano Pellicelli 39, Massimo Marignani 40, Luigi Muratori 41, Grazia Anna Niro 42, Maurizia Brunetto 43, Francesca Romana Ponziani 44, Maurizio Pompili 44, Fabio Marra 45, Andrea Galli 45, Alessandro Mussetto 46, Giuliano Alagna 47, Loredana Simone 48, Gaetano Bertino 49, Floriano Rosina
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33. | Pursuing living donor liver transplantation improves outcomes of patients with autoimmune liver diseases - An intention-to-treat analysis |
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Liver Transpl. 2024 Apr 16. doi: 10.1097/LVT.0000000000000374. Online ahead of print.
Owen Jones 1, Marco Paw Claasen 1 2, Tommy Ivanics 1 3 4, Woo Jin Choi 1 5, Felipe Gavaria 1, Luckshi Rajendran 1 5, Anand Ghanekar 1, Gideon Hirschfield 1, Aliya Gulamhusein 1, Chaya Shwaartz 1, Trevor Reichman 1, Blayne Amir Sayed 1, Markus Selzner 1, Mamatha Bhat 1, Cynthia Tsien 1, Elmar Jaeckel 1, Les Lilly 1, Ian D McGilvray 1, Mark S Cattral 1, Nazia Selzner 1, Gonzalo Sapisochin 1
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36. | A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis |
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Hepatology. 2024 Apr 23. doi: 10.1097/HEP.0000000000000894. Online ahead of print.
Yuki Hitomi 1, Kazuko Ueno 2, Yoshihiro Aiba 3, Nao Nishida 4 5, Michihiro Kono 6, Mitsuki Sugihara 7, Yosuke Kawai 2, Minae Kawashima 8, Seik-Soon Khor 2 9, Kazuhiro Sugi 10, Hirotaka Kouno 10, Hiroshi Kouno 10, Atsushi Naganuma 10, Satoru Iwamoto 10, Shinji Katsushima 10, Kiyoshi Furuta 10, Toshiki Nikami 10, Tomohiko Mannami 10, Tsutomu Yamashita 10, Keisuke Ario 10, Tatsuji Komatsu 10, Fujio Makita 10, Masaaki Shimada 10, Noboru Hirashima 10, Shiro Yokohama 10, Hideo Nishimura 10, Rie Sugimoto 10, Takuya Komura 10, Hajime Ota 10, Motoyuki Kojima 10, Makoto Nakamuta 10, Naoyuki Fujimori 10, Kaname Yoshizawa 10, Yutaka Mano 10, Hironao Takahashi 10, Kana Hirooka 10, Satoru Tsuruta 10, Takeaki Sato 10, Kazumi Yamasaki 3, Yuki Kugiyama 3, Yasuhide Motoyoshi 3, Tomoyuki Suehiro 3, Akira Saeki 3, Kosuke Matsumoto 3, Shinya Nagaoka 3, Seigo Abiru 3, Hiroshi Yatsuhashi 3, Masahiro Ito 3, Kazuhito Kawata 11, Akinobu Takaki 12, Kuniaki Arai 13, Teruko Arinaga 14, Masanori Abe 15, Masaru Harada 16, Makiko Taniai 17, Mikio Zeniya 18, Hiromasa Ohira 19, Shinji Shimoda 20, Atsumasa Komori
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37. | Primary biliary cholangitis drug evaluation and regulatory approval: Where do we go from here? |
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Hepatology. 2024 Mar 22. doi: 10.1097/HEP.0000000000000864. Online ahead of print.
David Ej Jones 1, Ulrich Beuers 2, Alan Bonder 3, Marco Carbone 4, Emma Culver 5, Jessica Dyson 6, Robert G Gish 7, Bettina E Hansen 8, Gideon Hirschfield 9, Rebecca Jones 10, Kris Kowdley 11, Andreas E Kremer 12, Keith Lindor 13, Marlyn Mayo 14, George Mells 15, James Neuberger 16, Martin Prince 17, Mark Swain 18, Atsushi Tanaka 19, Douglas Thorburn 20, Michael Trauner 21, Palak Trivedi 22, Martin Weltman 23, Andrew Yeoman 24, Cynthia Levy 25
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39. | Pruritus in primary biliary cholangitis is under-recorded in patient medical records |
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BMJ Open Gastroenterol. 2024 Mar 27;11(1):e001287. doi: 10.1136/bmjgast-2023-001287.
Usha Gungabissoon 1, Helen T Smith 2, Robyn von Maltzahn 2, John Logie 2, Jolyon Fairburn-Beech 2, Liyuan Ma 3, Dhirishiya P 4, Ashleigh McGirr 5, Jake N Hunnicutt 3, Christopher L Rowe 6, Meghan Tierney 6, Haley S Friedler 6
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40. | Osteoporosis and Primary Biliary Cholangitis: A Trans-ethnic Mendelian Randomization Analysis |
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Clin Rev Allergy Immunol. 2024 Mar 30. doi: 10.1007/s12016-024-08986-4.Online ahead of print.
Yi Wu # 1, Qiwei Qian # 1, Qiaoyan Liu 1, Rui Wang 1, Xiting Pu 1, Yao Li 1, Huayang Zhang 1, Zhengrui You 1, Qi Miao 1, Xiao Xiao 1, Min Lian 1, Qixia Wang 1, Minoru Nakamura 2, M Eric Gershwin 3, Zhiqiang Li 4 5, Xiong Ma 6 7, Ruqi Tang 8
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41. | Primary biliary cholangitis drug evaluation and regulatory approval: Where do we go from here? |
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Hepatology. 2024 Mar 22. doi: 10.1097/HEP.0000000000000864. Online ahead of print.
David Ej Jones 1, Ulrich Beuers 2, Alan Bonder 3, Marco Carbone 4, Emma Culver 5, Jessica Dyson 6, Robert G Gish 7, Bettina E Hansen 8, Gideon Hirschfield 9, Rebecca Jones 10, Kris Kowdley 11, Andreas E Kremer 12, Keith Lindor 13, Marlyn Mayo 14, George Mells 15, James Neuberger 16, Martin Prince 17, Mark Swain 18, Atsushi Tanaka 19, Douglas Thorburn 20, Michael Trauner 21, Palak Trivedi 22, Martin Weltman 23, Andrew Yeoman 24, Cynthia Levy 25
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43. | A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis |
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N Engl J Med. 2024 Feb 21. doi: 10.1056/NEJMoa2312100. Online ahead of print.
Gideon M Hirschfield 1, Christopher L Bowlus 1, Marlyn J Mayo 1, Andreas E Kremer 1, John M Vierling 1, Kris V Kowdley 1, Cynthia Levy 1, Alejandra Villamil 1, Alma L Ladrón de Guevara Cetina 1, Ewa Janczewska 1, Ehud Zigmond 1, Sook-Hyang Jeong 1, Yusuf Yilmaz 1, Yiannis Kallis 1, Christophe Corpechot 1, Peter Buggisch 1, Pietro Invernizzi 1, Maria Carlota Londoño Hurtado 1, Sandrin Bergheanu 1, Ke Yang 1, Yun-Jung Choi 1, Daria B Crittenden 1, Charles A McWherter 1; RESPONSE Study Group
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48. | Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: To what extent and under what conditions is normal alkaline phosphatase level associated with complication-free survival gain? |
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Hepatology. 2024 Jan 1;79(1):39-48. doi: 10.1097/HEP.0000000000000529. Epub 2023 Jul 3.
Christophe Corpechot 1, Sara Lemoinne 1, Pierre-Antoine Soret 1, Bettina Hansen 2 3, Gideon Hirschfield 3, Aliya Gulamhusein 3, Aldo J Montano-Loza 4, Ellina Lytvyak 5, Albert Pares 6, Ignasi Olivas 6, John E Eaton 7, Karim T Osman 7, Christoph Schramm 8, Marcial Sebode 8, Ansgar W Lohse 8, George Dalekos 9, Nikolaos Gatselis 9, Frederik Nevens 10, Nora Cazzagon 11, Alessandra Zago 11, Francesco Paolo Russo 11, Annarosa Floreani 11, Nadir Abbas 12, Palak Trivedi 13, Douglas Thorburn 14, Francesca Saffioti 14, Laszlo Barkai 14, Davide Roccarina 14, Vicenza Calvaruso 15, Anna Fichera 15, Adèle Delamarre 16, Natalia Sobenko 17, Alejandra Maria Villamil 17, Esli Medina-Morales 18, Alan Bonder 18, Vilas Patwardhan 18, Cristina Rigamonti 19, Marco Carbone 20, Pietro Invernizzi 20, Laura Cristoferi 20, Adriaan van der Meer 21, Rozanne de Veer 21, Ehud Zigmond 22, Eyal Yehezkel 22, Andreas E Kremer 23, Ansgar Deibel 23, Tony Bruns 24, Karsten Große 24, Aaron Wetten 25, Jessica Katharine Dyson 25, David Jones 25, Jérôme Dumortier 26, Georges-Philippe Pageaux 27, Victor de Lédinghen 16, Olivier Chazouillères 1, Fabrice Carrat 28 29; Global & ERN Rare-Liver PBC Study Groups
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53. | Adequate versus deep response to ursodeoxycholic acid in primary biliary cholangitis: To what extent and under what conditions is normal alkaline phosphatase level associated with complication-free survival gain? |
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Hepatology. 2024 Jan 1;79(1):39-48. doi: 10.1097/HEP.0000000000000529. Epub 2023 Jul 3.
Christophe Corpechot 1, Sara Lemoinne 1, Pierre-Antoine Soret 1, Bettina Hansen 2 3, Gideon Hirschfield 3, Aliya Gulamhusein 3, Aldo J Montano-Loza 4, Ellina Lytvyak 5, Albert Pares 6, Ignasi Olivas 6, John E Eaton 7, Karim T Osman 7, Christoph Schramm 8, Marcial Sebode 8, Ansgar W Lohse 8, George Dalekos 9, Nikolaos Gatselis 9, Frederik Nevens 10, Nora Cazzagon 11, Alessandra Zago 11, Francesco Paolo Russo 11, Annarosa Floreani 11, Nadir Abbas 12, Palak Trivedi 13, Douglas Thorburn 14, Francesca Saffioti 14, Laszlo Barkai 14, Davide Roccarina 14, Vicenza Calvaruso 15, Anna Fichera 15, Adèle Delamarre 16, Natalia Sobenko 17, Alejandra Maria Villamil 17, Esli Medina-Morales 18, Alan Bonder 18, Vilas Patwardhan 18, Cristina Rigamonti 19, Marco Carbone 20, Pietro Invernizzi 20, Laura Cristoferi 20, Adriaan van der Meer 21, Rozanne de Veer 21, Ehud Zigmond 22, Eyal Yehezkel 22, Andreas E Kremer 23, Ansgar Deibel 23, Tony Bruns 24, Karsten Große 24, Aaron Wetten 25, Jessica Katharine Dyson 25, David Jones 25, Jérôme Dumortier 26, Georges-Philippe Pageaux 27, Victor de Lédinghen 16, Olivier Chazouillères 1, Fabrice Carrat 28 29; Global & ERN Rare-Liver PBC Study Groups
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54. | Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis |
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Aliment Pharmacol Ther. 2024 Jan;59(2):186-200. doi: 10.1111/apt.17755. Epub 2023 Oct 30.
Marlyn J Mayo 1, John M Vierling 2, Christopher L Bowlus 3, Cynthia Levy 4 5, Gideon M Hirschfield 6, Guy W Neff 7, Michael R Galambos 8, Stuart C Gordon 9, Brian B Borg 10, Stephen A Harrison 11, Paul J Thuluvath 12 13, Aparna Goel 14, Mitchell L Shiffman 15, Mark G Swain 16, David E J Jones 17, Palak Trivedi 18, Andreas E Kremer 19, Richard J Aspinall 20, David A Sheridan 21, Yvonne Dörffel 22, Ke Yang 23, Yun-Jung Choi 24, Charles A McWherter 24
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57. | Critical shortfalls in the management of PBC: Results of a UK-wide, population-based evaluation of care delivery |
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JHEP Rep. 2023 Oct 16;6(1):100931. doi: 10.1016/j.jhepr.2023.100931. eCollection 2024 Jan.
Nadir Abbas 1 2 3, Rachel Smith 4 5, Steven Flack 4, Vikram Bains 5, Richard J Aspinall 6, Rebecca L Jones 7, Laura Burke 7, Douglas Thorburn 8, Michael Heneghan 9, Andrew Yeoman 10, Joanna Leithead 11, Conor Braniff 12, Andrew Robertson 13, Chris Mitchell 14, Collette Thain 14, Robert Mitchell-Thain 15, David Jones 16 17, Palak J Trivedi 1 2 3 18, George F Mells 4 5, Laith Alrubaiy 19 20; UK-PBC audit group
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59. | Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis |
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N Engl J Med. 2023 Nov 13. doi: 10.1056/NEJMoa2306185. Online ahead of print.
Kris V Kowdley 1, Christopher L Bowlus 1, Cynthia Levy 1, Ulus S Akarca 1, Mario Reis Alvares-da-Silva 1, Pietro Andreone 1, Marco Arrese 1, Christophe Corpechot 1, Sven M Francque 1, Michael A Heneghan 1, Pietro Invernizzi 1, David Jones 1, Frederik C Kruger 1, Eric Lawitz 1, Marlyn J Mayo 1, Mitchell L Shiffman 1, Mark G Swain 1, José Miguel Valera 1, Victor Vargas 1, John M Vierling 1, Alejandra Villamil 1, Carol Addy 1, Julie Dietrich 1, Jean-Michel Germain 1, Sarah Mazain 1, Dragutin Rafailovic 1, Bachirou Taddé 1, Benjamin Miller 1, Jianfen Shu 1, Claudia O Zein 1, Jörn M Schattenberg 1; ELATIVE Study Investigators’ Group
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60. | Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis |
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Aliment Pharmacol Ther. 2023 Oct 30. doi: 10.1111/apt.17755. Online ahead of print.
Marlyn J Mayo 1, John M Vierling 2, Christopher L Bowlus 3, Cynthia Levy 4 5, Gideon M Hirschfield 6, Guy W Neff 7, Michael R Galambos 8, Stuart C Gordon 9, Brian B Borg 10, Stephen A Harrison 11, Paul J Thuluvath 12 13, Aparna Goel 14, Mitchell L Shiffman 15, Mark G Swain 16, David E J Jones 17, Palak Trivedi 18, Andreas E Kremer 19, Richard J Aspinall 20, David A Sheridan 21, Yvonne Dörffel 22, Ke Yang 23, Yun-Jung Choi 24, Charles A McWherter 24
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63. | Risk Stratification in Primary Biliary Cholangitis |
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J Clin Med. 2023 Sep 1;12(17):5713. doi: 10.3390/jcm12175713.
Francesco Martini 1, Daniele Balducci 1, Martina Mancinelli 1, Valerio Buzzanca 1, Elena Fracchia 1, Giuseppe Tarantino 1, Antonio Benedetti 1, Marco Marzioni 1, Luca Maroni 1
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64. | Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study |
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Hepatology. 2023 Aug 1;78(2):397-415. doi: 10.1097/HEP.0000000000000395.Epub 2023 Apr 6.
Gideon M Hirschfield 1, Mitchell L Shiffman 2 3, Aliya Gulamhusein 4, Kris V Kowdley 5, John M Vierling 6, Cynthia Levy 7, Andreas E Kremer 8, Ehud Zigmond 9, Pietro Andreone 10 11, Stuart C Gordon 12, Christopher L Bowlus 13, Eric J Lawitz 14, Richard J Aspinall 15, Daniel S Pratt 16, Karina Raikhelson 17 18, Maria S Gonzalez-Huezo 19, Michael A Heneghan 20, Sook-Hyang Jeong 21, Alma L Ladrón de Guevara 22, Marlyn J Mayo 23, George N Dalekos 24, Joost P H Drenth 25, Ewa Janczewska 26 27, Barbara A Leggett 28, Frederik Nevens 29 30, Victor Vargas 31 32, Eli Zuckerman 33, Christophe Corpechot 34, Eduardo Fassio 35, Holger Hinrichsen 36, Pietro Invernizzi 37 38, Palak J Trivedi 39 40 41 42, Lisa Forman 43, David E J Jones 44, Stephen D Ryder 45, Mark G Swain 46, Alexandra Steinberg 47, Pol F Boudes 47, Yun-Jung Choi 47, Charles A McWherter 47; ENHANCE Study Group*
Collaborators
Raul Adrover, Saurabh Agrawal, Elmar Aigner, Agustin A Martinez, Abu-Mouch S Alden, Raul Jesús Andrade Bellido, Marco Antonio Arrese Jiménez, Walid Ayoub, Seth J Baum, Ziv Ben-Ari, Marina Berenguer, Christoph Berg, Fernando O Bessone, Alan Bonder, Brian B Borg, Carlos Gustavo Bresky Ruiz, Peter Buggisch, Jose Luis Calleja Panero, Elizabeth J Carey, Michal Carmiel-Haggai, Francesca Carubbi, Pilar Castillo Grau, Chin L Ch'ng, Nicoleta-Claudia Cimpoeru, Raúl C Omaña, Lynsey Corless, Charlotte Costentin, Marc Deschênes, Yvonne Dörffel, Predrag Dugalic, Geoffrey C Farrell, José L Fernández, Annarosa Floreani, Sven Francque, Bradley L Freilich, Francisco Alejandro Fuster Saldias, Michael R Galambos, Joseph Galati, Andrea Galli, Nathalie Ganne-Carrie, Natalia Geyvandova, Liliana-Simona Gheorghe, Richard Gilroy, Aparna Goel, Tobias Goeser, Susan Greenbloom, Waldemar Halota, Stephen A Harrison, Marek Hartleb, Jeong Heo, Harald Hofer, Gábor Horváth, Jonathan C Huang, Jason L Huffman, Béla Hunyady, Steven Johnson, Yiannis Kallis, Arun Khazanchi,
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68. | Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis |
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JHEP Rep. 2023 Apr 29;5(8):100782. doi: 10.1016/j.jhepr.2023.100782. eCollection 2023 Aug.
Richard J Thompson 1, Reha Artan 2, Ulrich Baumann 3, Pier Luigi Calvo 4, Piotr Czubkowski 5, Buket Dalgic 6, Lorenzo D'Antiga 7, Angelo Di Giorgio 7, Özlem Durmaz 8, Emmanuel Gonzalès 9, Tassos Grammatikopoulos 1 10, Girish Gupte 11, Winita Hardikar 12, Roderick H J Houwen 13, Binita M Kamath 14, Saul J Karpen 15, Florence Lacaille 16, Alain Lachaux 17, Elke Lainka 18, Kathleen M Loomes 19, Cara L Mack 20, Jan P Mattsson 21, Patrick McKiernan 11, Quanhong Ni 21, Hasan Özen 22, Sanjay R Rajwal 23, Bertrand Roquelaure 24, Eyal Shteyer 25, Etienne Sokal 26, Ronald J Sokol 27, Nisreen Soufi 28, Ekkehard Sturm 29, Mary Elizabeth Tessier 30, Wendy L van der Woerd 13, Henkjan J Verkade 31, Jennifer M Vittorio 32, Terese Wallefors 21, Natalie Warholic 21, Qifeng Yu 21, Patrick Horn 21, Lise Kjems 21
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70. | Adequate vs. deep response to UDCA in PBC: To what extent and under what conditions is normal ALP level associated with complication-free survival gain? |
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Hepatology. 2023 Jul 3. doi: 10.1097/HEP.0000000000000529. Online ahead of print.
Christophe Corpechot 1, Sara Lemoinne 1, Pierre-Antoine Soret 1, Bettina Hansen 2 3, Gideon Hirschfield 3, Aliya Gulamhusein 3, Aldo J Montano-Loza 4, Ellina Lytvyak 5, Albert Pares 6, Ignasi Olivas 6, John E Eaton 7, Karim T Osman 7, Christoph Schramm 8, Marcial Sebode 8, Ansgar W Lohse 8, George Dalekos 9, Nikolaos Gatselis 9, Frederik Nevens 10, Nora Cazzagon 11, Alessandra Zago 11, Francesco Paolo Russo 11, Annarosa Floreani 11, Nadir Abbas 12, Palak Trivedi 13, Douglas Thorburn 14, Francesca Saffioti 14, Laszlo Barkai 14, Davide Roccarina 14, Vicenza Calvaruso 15, Anna Fichera 15, Adèle Delamarre 16, Natalia Sobenko 17, Alejandra Maria Villamil 17, Esli Medina-Morales 18, Alan Bonder 18, Vilas Patwardhan 18, Cristina Rigamonti 19, Marco Carbone 20, Pietro Invernizzi 20, Laura Cristoferi 20, Adriaan van der Meer 21, Rozanne de Veer 21, Ehud Zigmond 22, Eyal Yehezkel 22, Andreas E Kremer 23, Ansgar Deibel 23, Tony Bruns 24, Karsten Große 24, Aaron Wetten 25, Jessica Katharine Dyson 25, David Jones 25, Jérôme Dumortier 26, Georges-Philippe Pageaux 27, Victor de Lédinghen 16, Olivier Chazouillères 1, Fabrice Carrat 28; Global & ERN Rare-Liver PBC Study Groups
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71. | Ursodeoxycholic Acid Treatment-Induced GLOBE Score Changes Are Associated With Liver Transplantation-Free Survival in Patients With Primary Biliary Cholangitis |
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Am J Gastroenterol. 2023 Jul 1;118(7):1196-1203. doi: 10.14309/ajg.0000000000002128.Epub 2022 Dec 14.
Rozanne C de Veer 1, Maria C van Hooff 1, Christophe Corpechot 2, Douglas Thorburn 3, Pietro Invernizzi 4 5, Willem J Lammers 1, Harry L A Janssen 1 6, Pier M Battezzati 7, Frederik Nevens 8, Keith D Lindor 8 9 10, Annarosa Floreani 11 12, Cyriel Y Ponsioen 13, Marlyn J Mayo 14, Albert Parés 15, Andrew L Mason 16, Kris V Kowdley 17, Palak J Trivedi 18, Gideon M Hirschfield 6 18, Jorn C Goet 1, Tony Bruns 19 20, George N Dalekos 21 22, Nikolaos K Gatselis 21 22, Xavier Verhelst 23, Bettina E Hansen 1 6, Maren H Harms 1, Adriaan J van der Meer 1; Global PBC Study Group
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72. | Excellent outcome in patients with primary biliary cholangitis in Northwest Italy followed up for up to 30 years |
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Eur J Gastroenterol Hepatol. 2023 Aug 1;35(8):899-906.doi: 10.1097/MEG.0000000000002582. Epub 2023 Jun 6.
Cristina Rigamonti 1, Carla De Benedittis 1, Sara Labanca 2, Ester Vanni 3, Anna Morgando 3, Giulia Francesca Manfredi 1, Danila Azzolina 4, Micol Giulia Cittone 1, Edoardo Giovanni Giannini 2, Giorgio Maria Saracco 3, Mario Pirisi 1
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75. | GLIMMER: A Randomized Phase 2b Dose-Ranging Trial of Linerixibat in Primary Biliary Cholangitis Patients With Pruritus |
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Clin Gastroenterol Hepatol. 2023 Jul;21(7):1902-1912.e13.doi: 10.1016/j.cgh.2022.10.032. Epub 2022 Nov 4.
Cynthia Levy 1, Stuart Kendrick 2, Christopher L Bowlus 3, Atsushi Tanaka 4, David Jones 5, Andreas E Kremer 6, Marlyn J Mayo 7, Nazneen Haque 2, Robyn von Maltzahn 8, Matthew Allinder 9, Brandon Swift 10, Megan M McLaughlin 9, Gideon M Hirschfield 11; GLIMMER Study Group
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80. | ACR Appropriateness Criteria® Right Upper Quadrant Pain: 2022 Update |
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J Am Coll Radiol. 2023 May;20(5S):S211-S223.doi: 10.1016/j.jacr.2023.02.011.
Expert Panel on Gastrointestinal Imaging; Gregory K Russo 1, Atif Zaheer 2, Ihab R Kamel 3, Kristin K Porter 4, Krystal Archer-Arroyo 5, Mustafa R Bashir 6, Brooks D Cash 7, Alice Fung 8, Marion McCrary 9, Brendan M McGuire 10, Richard D Shih 11, John Stowers 12, Kiran H Thakrar 13, Abhinav Vij 14, Shaun A Wahab 15, Katherine Zukotynski 16, Laura R Carucci 17
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81. | The association between soluble CD163, disease severity, and ursodiol treatment in patients with primary biliary cholangitis |
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Hepatol Commun. 2023 Mar 24;7(4):e0068. doi: 10.1097/HC9.0000000000000068.eCollection 2023 Apr 1.
Lars Bossen 1, Tobias Stemann Lau 1, Mette Bak Nielsen 2, Marlene Christina Nielsen 3, Astrid Højmark Andersen 1, Peter Ott 1, Sabine Becker 4, Henning Glerup 4, Lise Svenningsen 5, Martin Eivindson 5, Linda Kornerup 1 6, Niels Bjørndal Kjeldsen 7, Anders Neumann 8, Holger Jon Møller 3, Peter Jepsen 1, Henning Grønbæk 1
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82. | Optimizing therapy in primary biliary cholangitis: Alkaline phosphatase at six months identifies one-year non-responders and predicts survival |
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Liver Int. 2023 May 8. doi: 10.1111/liv.15592. Online ahead of print.
C Fiorella Murillo Perez 1, Stephanie Ioannou 2, Iman Hassanally 3, Palak J Trivedi 4, Christophe Corpechot 5, Adriaan J van der Meer 6, Willem J Lammers 6, Pier Maria Battezzati 7, Keith D Lindor 8, Frederik Nevens 9, Kris V Kowdley 10, Tony Bruns 11, Nora Cazzagon 12, Annarosa Floreani 12 13, Andrew L Mason 14, Aliya Gulamhusein 1, Cyriel Y Ponsioen 15, Marco Carbone 16, Ana Lleo 17, Marlyn J Mayo 18, George N Dalekos 19, Nikolaos K Gatselis 19, Douglas Thorburn 20, Xavier Verhelst 21, Albert Parés 22, Maria-Carlota Londoño 22, Harry L A Janssen 1 6, Pietro Invernizzi 16, Raj Vuppalanchi 23, Gideon M Hirschfield 1, Bettina E Hansen 1 3 6, Cynthia Levy 2; Global PBC Study Group
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84. | Regulation of immune responses in primary biliary cholangitis: a transcriptomic analysis of peripheral immune cells |
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Hepatol Commun. 2023 Apr 4;7(4):e0110. doi: 10.1097/HC9.0000000000000110.eCollection 2023 Apr 1.
Victoria Mulcahy 1 2, Evaggelia Liaskou 3 4, Jose-Ezequiel Martin 1 5, Prasanti Kotagiri 6 7, Jonathan Badrock 1, Rebecca L Jones 8, Simon M Rushbrook 9, Stephen D Ryder 10, Douglas Thorburn 11, Simon D Taylor-Robinson 12, Graeme Clark 13, Heather J Cordell 14, Richard N Sandford 1, David E Jones 15 16, Gideon M Hirschfield 17, George F Mells 1 2
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87. | Response to Ursodeoxycholic Acid May Be Assessed Earlier to Allow Second-Line Therapy in Patients with Unresponsive Primary Biliary Cholangitis |
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Dig Dis Sci. 2023 Feb;68(2):514-520. doi: 10.1007/s10620-022-07654-x.Epub 2022 Aug 22.
Guilherme Grossi Lopes Cançado 1 2, Cláudia Alves Couto 3, Debora Raquel Benedita Terrabuio 4, Eduardo Luiz Rachid Cançado 4, Cristiane Alves Villela-Nogueira 5, Maria Lucia Gomes Ferraz 6, Michelle Harriz Braga 4, Mateus Jorge Nardelli 3, Luciana Costa Faria 3, Nathalia Mota de Faria Gomes 6, Elze Maria Gomes Oliveira 7, Vivian Rotman 5, Maria Beatriz Oliveira 8, Simone Muniz Carvalho Fernandes da Cunha 9, Marlone Cunha-Silva 10, Liliana Sampaio Costa Mendes 11, Claudia Alexandra Pontes Ivantes 12, Liana Codes 9 13, Valéria Ferreira de Almeida E Borges 14 15, Fabio Heleno de Lima Pace 16, Mario Guimarães Pessoa 4, Laura Vilar Guedes 4, Izabelle Venturini Signorelli 17, Gabriela Perdomo Coral 18, Cynthia Levy 19, Paulo Lisboa Bittencourt 13 20; Members of the Brazilian Cholestasis Study Group Consortium
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101. | The unhealthy lifestyle in primary biliary cholangitis: An enemy to fight |
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Dig Liver Dis. 2022 Dec 31;S1590-8658(22)00833-7. doi: 10.1016/j.dld.2022.12.009.Online ahead of print.
Valentina Cossiga 1, Nora Cazzagon 2, Roberto Montalti 3, Stefania Ciminnisi 4, Maria Rosaria Attanasio 5, Francesco Pezzato 6, Marco Giacchetto 4, Maria Guarino 5, Vincenza Calvaruso 4, Annarosa Floreani 7, Filomena Morisco 5
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102. | Greater Transplant-Free Survival in Patients Receiving Obeticholic Acid for Primary Biliary Cholangitis in a Clinical Trial Setting Compared to Real-World External Controls |
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Gastroenterology. 2022 Dec;163(6):1630-1642.e3.doi: 10.1053/j.gastro.2022.08.054. Epub 2022 Sep 20.
C Fiorella Murillo Perez 1, Holly Fisher 2, Shaun Hiu 2, Dorcas Kareithi 2, Femi Adekunle 3, Tracy Mayne 3, Elizabeth Malecha 3, Erik Ness 3, Adriaan J van der Meer 4, Willem J Lammers 4, Palak J Trivedi 5, Pier Maria Battezzati 6, Frederik Nevens 7, Kris V Kowdley 8, Tony Bruns 9, Nora Cazzagon 10, Annarosa Floreani 10, Andrew L Mason 11, Albert Parés 12, Maria-Carlota Londoño 12, Pietro Invernizzi 13, Marco Carbone 14, Ana Lleo 15, Marlyn J Mayo 16, George N Dalekos 17, Nikolaos K Gatselis 17, Douglas Thorburn 18, Xavier Verhelst 19, Aliya Gulamhusein 1, Harry L A Janssen 20, Rachel Smith 21, Steve Flack 22, Victoria Mulcahy 22, Michael Trauner 23, Christopher L Bowlus 24, Keith D Lindor 25, Christophe Corpechot 26, David Jones 2, George Mells 27, Gideon M Hirschfield 1, James Wason 28, Bettina E Hansen 29; GLOBAL PBC Study Group and the members of the UK-PBC Consortium
Collaborators
- GLOBAL PBC Study Group and the members of the UK-PBC Consortium:
Richard Sturgess, Christopher Healey, Anton Gunasekera, Yiannis Kallis, Gavin Wright, Thiriloganathan Mathialahan, Richard Evans, Jaber Gasem, David Ramanaden, Emma Ward, Mahesh Bhalme, Paul Southern, James Maggs, Mohamed Yousif, George Mells, Brijesh Srivastava, Matthew Foxton, Carole Collins, Yash Prasad, Francisco Porras-Perez, Tom Yapp, Minesh Patel, Roland Ede, Martyn Carte, Konrad Koss, Prayman Sattianayagam, Charles Grimley, Jude Tidbury, Dina Mansour, Matilda Beckley, Coral Hollywood, John Ramag, Harriet Gordon, Joanne Ridpath, Bob Grover, George Abouda, Ian Rees, Mark Narain, Imroz Salam, Paul Banim, Debasish Das, Helen Matthews, Faiyaz Mohammed, Rebecca Jones, Sambit Sen, George Bird, Martin Prince, Geeta Prasad, Paul Kitchen, John Hutchinson, Prakash Gupta, David Jones, Amir Shah, Subrata Saha, Katharine Pollock, Stephen Barclay, Natasha McDonald, Simon Rushbrook, Robert Przemioslo, Andrew Millar, Steven Mitchell, Andrew Davis, Asifabbas Naqvi, Tom Lee, Stephen Ryder, Jane Collier, Matthew Cramp, Richard Aspinal, Jonathan Booth, Earl Williams, Hyder Hussaini, John Christie, Tehreem Chaudhry, Douglas Thorburn, Stephen Mann, Aftab Ala, Julia Maltby, Chris Corbett, Saket Singhal, Barbara Hoeroldt, Jeff Butterworth, Andrew Douglas, Rohit Sinha, Simon Panter, Jeremy Shearman, Gary Bray, Michael Roberts, Daniel Forton, Nicola Taylor, Wisam Jafar, Matthew Cowan, Chin Lye Ch'ng, Mesbah Rahman, Emma Wesley, Sanjiv Jain, Aditya Mandal, Mark Wright, Palak Trivedi, Fiona Gordon, Esther Unitt, Andrew Austin, Altaf Palegwala, Vishwaraj Vemala, Andrew Higham, Jocelyn Fraser, Andy Li, Subramaniam Ramakrishnan, Alistair King, Simon Whalley, Ian Gee, Richard Keld, Helen Fellows, James Gotto, Charles Millson
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103. | Neurosteroid Activation of GABA-A Receptors: A Potential Treatment Target for Symptoms in Primary Biliary Cholangitis? |
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Can J Gastroenterol Hepatol. 2022 Dec 6;2022:3618090. doi: 10.1155/2022/3618090.eCollection 2022.
Aaron Wetten 1 2, Laura Ogle 1 2, George Mells 3, Vinod S Hegade 4, Laura Jopson 1 2, Margaret Corrigan 5, Jeremy Palmer 1, Maja Johansson 6, Torbjörn Bäckström 6 7, Magnus Doverskog 6, David E J Jones 1 2, Jessica K Dyson 1 2
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108. | Farnesoid X receptor agonist tropifexor attenuates cholestasis in a randomised trial in patients with primary biliary cholangitis |
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JHEP Rep. 2022 Jul 21;4(11):100544. doi: 10.1016/j.jhepr.2022.100544. eCollection 2022 Nov.
Christoph Schramm 1 2 3, Heiner Wedemeyer 4, Andrew Mason 5, Gideon M Hirschfield 6, Cynthia Levy 7, Kris V Kowdley 8, Piotr Milkiewicz 9 10, Ewa Janczewska 11 12, Elena Sergeevna Malova 13, Johanne Sanni 14 15, Phillip Koo 16, Jin Chen 16, Subhajit Choudhury 17, Lloyd B Klickstein 18, Michael K Badman 18, David Jones 19
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115. | TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation |
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J Hepatol. 2022 Oct;77(4):991-1004. doi: 10.1016/j.jhep.2022.05.044. Epub 2022 Jun 22.
Ibone Labiano 1, Aloña Agirre-Lizaso 1, Paula Olaizola 1, Anne Echebarria 1, Maider Huici-Izagirre 1, Irene Olaizola 1, Aitor Esparza-Baquer 1, Omar Sharif 2, Elizabeth Hijona 3, Piotr Milkiewicz 4, Malgorzata Milkiewicz 5, Francisco González-Romero 6, Patricia Aspichueta 7, Maria J Monte 8, Jose J G Marin 8, Mihael Vucur 9, Tom Luedde 9, Marco Marzioni 10, Derek A Mann 11, Luis Bujanda 12, Pedro M Rodrigues 13, Jesus M Banales 14, Maria J Perugorria 15
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120. | High Prevalence of Lower Limb Atherosclerosis is Linked with the Gut-Liver-Axis in Patients with Primary Biliary Cholangitis |
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Liver Int. 2022 Oct 26. doi: 10.1111/liv.15463. Online ahead of print.
Francesca Romana Ponziani 1 2, Antonio Nesci 3, Camilla Caputo 1, Lucia Salvatore 1, Anna Picca 4, Federica Del Chierico 5, Francesco Paroni Sterbini 6, Emanuele Marzetti 4, Angela Di Giorgio 3, Luca Santoro 3, Lorenza Putignani 5 7, Antonio Gasbarrini 1 2, Angelo Santoliquido # 3 2, Maurizio Pompili # 1 2
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122. | UK-wide Multicenter Evaluation of Second-line Therapies in Primary Biliary Cholangitis |
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Clin Gastroenterol Hepatol. 2022 Aug 9;S1542-3565(22)00738-8.doi: 10.1016/j.cgh.2022.07.038. Online ahead of print.
Nadir Abbas 1, Emma L Culver 2, Douglas Thorburn 3, Neil Halliday 3, Hannah Crothers 4, Jessica K Dyson 5, April Phaw 5, Richard Aspinall 6, Salim I Khakoo 7, Yiannis Kallis 8, Belinda Smith 9, Imran Patanwala 10, Anne McCune 11, Chenchu R Chimakurthi 12, Vinod Hegade 12, Michael Orrell 2, Rebecca Jones 12, George Mells 13, Colette Thain 14, Robert-Mitchell Thain 14, David Jones 5, Gideon Hirschfield 15, Palak J Trivedi 16
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123. | Predictors of serious adverse events and non-response in cirrhotic patients with primary biliary cholangitis treated with obeticholic acid |
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Liver Int. 2022 Nov;42(11):2453-2465. doi: 10.1111/liv.15386. Epub 2022 Aug 23.
Antonio De Vincentis 1, Daphne D'Amato 2, Laura Cristoferi 3, Alessio Gerussi 3, Federica Malinverno 3, Ana Lleo 4, Francesca Colapietro 4, Fabio Marra 5, Andrea Galli 6, Cecilia Fiorini 6, Barbara Coco 7, Maurizia Brunetto 7, Grazia Anna Niro 8, Rosa Cotugno 8, Carlo Saitta 9, Raffaele Cozzolongo 10, Francesco Losito 10, Edoardo Giovanni Giannini 11, Sara Labanca 11, Marco Marzioni 12, Giulia Marconi 12, Anna Morgando 2, Rinaldo Pellicano 2, Ester Vanni 2, Nora Cazzagon 13, Annarosa Floreani 13, Luchino Chessa 14, Olivia Morelli 15, Luigi Muratori 16, Adriano Pellicelli 17, Maurizio Pompili 18, Francesca Ponziani 18, Annalisa Tortora 18, Floriano Rosina 19, Maurizio Russello 20, Mariarita Cannavò 20, Loredana Simone 21, Silvia Storato 22, Mauro Viganò 23, Ludovico Abenavoli 24, Maria D'Antò 25, Elisabetta De Gasperi 26, Marco Distefano 27, Gaetano Scifo 27, Teresa Zolfino 28, Vincenza Calvaruso 29, Giuseppe Cuccorese 30, Valeria Pace Palitti 31, Rodolfo Sacco 32, Gaetano Bertino 33, Evelise Frazzetto 33, Domenico Alvaro 34, Giacomo Mulinacci 3, Andrea Palermo 3, Miki Scaravaglio 3, Francesca Terracciani 1, Giovanni Galati 1, Vincenzo Ronca 3, Massimo Zuin 35 36, Ernesto Claar 37, Antonio Izzi 38, Antonio Picardi 1, Pietro Invernizzi 3, Umberto Vespasiani-Gentilucci 1, Marco Carbone 3, on behalf of the Club Epatologi Ospedalieri (CLEO)/Associazione Italiana Gastroenterologi ed Endoscopisti Digestivi Ospedalieri (AIGO) PBC Study Group and, the Italian PBC Registry
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124. | Optimization of Laboratory Diagnostics of Primary Biliary Cholangitis: When Solid-Phase Assays and Immunofluorescence Combine |
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Clin Med. 2022 Sep 5;11(17):5238. doi: 10.3390/jcm11175238.
Federica Gaiani 1 2, Roberta Minerba 3, Alessandra Picanza 3, Annalisa Russo 3, Alessandra Melegari 4, Elena De Santis 4, Tommaso Trenti 5, Lucia Belloni 6, Silvia Peveri 7, Rosalia Aloe 3, Carlo Ferrari 1 8, Luigi Laghi 1 2, Gian Luigi de'Angelis 1 2, Chiara Bonaguri 3
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125. | Characteristics and survival of patients with primary biliary cholangitis and hepatocellular carcinoma |
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Dig Liver Dis. 2022 Sep;54(9):1215-1221. doi: 10.1016/j.dld.2022.03.002. Epub 2022 Mar 27.
Edoardo G Giannini 1, Giulia Pieri 2, Sara Labanca 2, Maria Corina Plaz Torres 2, Antonio Gasbarrini 3, Elisabetta Biasini 4, Claudia Campani 5, Nora Cazzagon 6, Francesco Giuseppe Foschi 7, Andrea Mega 8, Alberto Masotto 9, Giovanni Raimondo 10, Gian Ludovico Rapaccini 11, Rodolfo Sacco 12, Eugenio Caturelli 13, Maria Guarino 14, Francesco Tovoli 15, Gianpaolo Vidili 16, Maurizia Rossana Brunetto 17, Gerardo Nardone 18, Gianluca Svegliati-Baroni 19, Donatella Magalotti 20, Francesco Azzaroli 21, Giuseppe Cabibbo 22, Maria Di Marco 23, Angelo Sangiovanni 24, Franco Trevisani 25, Italian Liver Cancer (ITA.LI.CA) Study Group
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126. | Longitudinal Assessment of Bile Duct Loss in Primary Biliary Cholangitis |
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Am J Gastroenterol. 2022 Sep 1. doi: 10.14309/ajg.0000000000001985. Online ahead of print.
Julian Hercun 1, Mazen Noureddin 1, Nabil Noureddin 1, Jason Eccleston 1, Daniel Woolridge 1, T Jake Liang 1, Michele Tana 1, David E Kleiner 2, Gracia Viana Rodriguez 1, Christopher Koh 1, Jay H Hoofnagle 1, Theo Heller 1
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