:: CLDF ::

Recent advances in clinical practice: epidemiology of autoimmune liver diseases

Gut. 2021 Jul 15;gutjnl-2020-322362. doi: 10.1136/gutjnl-2020-322362.Online ahead of print.

Palak J Trivedi^1 2 3 4, Gideon M Hirschfield⁵

A consensus integrated care pathway for patients with primary biliary cholangitis: a guideline-based approach to clinical care of patients

Expert Rev Gastroenterol Hepatol. 2021 Jul 7;1-11. doi: 10.1080/17474124.2021.1945919.Online ahead of print.

Gideon M Hirschfield¹, Olivier Chazouillères², Helena Cortez-Pinto³, Guilherme Macedo⁴, Victor de Lédinghen⁵, Femi Adekunle⁶, Marco Carbone⁷

Baricitinib and primary biliary cholangitis

J Transl Autoimmun. 2021 Jun 1;4:100107. doi: 10.1016/j.jtauto.2021.100107. eCollection 2021.

Stuart C Gordon^1 2, Sheri Trudeau³, Arie Regev⁴, Jonathan M Uhas¹, Sujatro Chakladar⁴, Ana Pinto-Correia⁴, Klaus Gottlieb⁴, Doug Schlichting⁴

Obeticholic Acid and Fibrates in Primary Biliary Cholangitis: Comparative Effects in a Multicentric Observational Study

Am J Gastroenterol. 2021 Jun 23. doi: 10.14309/ajg.0000000000001343. Online ahead of print.

Anna Reig^1 2, Carmen Álvarez-Navascués³, Mercedes Vergara^2 4, Elena Gómez-Domínguez⁵, Adolfo Gallego-Moya⁶, Indhira M Pérez-Medrano⁷, Emilio Fábrega⁸, Manuel Hernández-Guerra⁹, Marina Berenguer^2 10 11, Pamela Estevez¹², Ana Arencibia¹³, Rosa M Morillas^2 14, Diana Horta¹⁵, Agustín Albillos^2 16, Marta Casado¹⁷, Gema De la Cruz¹⁸, Eva Fernandez-Bonilla¹⁹, Esther Molina²⁰, Lander Hijona²¹, Moises Diago²², Conrado M Fernández-Rodriguez²³, Jesús M González-Santiago²⁴, Margarita Sala^2 25, Judith Gómez-Camarero²⁶, Manuel Romero-Gomez^2 27, Francisco Suárez²⁸, Victor Vargas^2 29, Carlos Ferre-Aracil³⁰, Raúl J Andrade^2 31, Nadia Chahri³², Albert Parés^1 2

Affi

The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis

Hepatology. 2021 Jun 15. doi: 10.1002/hep.32011. Online ahead of print.

Ben Barron-Millar¹, Laura Ogle¹, George Mells², Steven Flack², Jonathan Badrock², Richard Sandford², John Kirby¹, Jeremy Palmer¹, Laura Jopson¹, John Brain¹, Graham R Smith³, Steve Rushton⁴, Vinod S Hegade⁵, Rebecca Jones⁵, Simon Rushbrook⁶, Douglas Thorburn⁷, Steve Ryder⁸, Gideon Hirschfield^9 10, UK-PBC Research Consortium; Jessica K Dyson^1 11, David Jones^1 11

An international genome-wide meta-analysis of primary biliary cholangitis: novel risk loci and candidate drugs

Heather J Cordell¹, James J Fryett¹, Kazuko Ueno², Rebecca Darlay¹, Yoshihiro Aiba³, Yuki Hitomi⁴, Minae Kawashima⁴, Nao Nishida⁴, Seik-Soon Khor², Olivier Gervais⁵, Yosuke Kawai², Masao Nagasaki⁵, Katsushi Tokunaga², Ruqi Tang⁶, Yongyong Shi⁷, Zhiqiang Li⁷, Brian D Juran⁸, Elizabeth J Atkinson⁹, Alessio Gerussi¹⁰, Marco Carbone¹⁰, Rosanna Asselta¹¹, Angela Cheung⁸, Mariza de Andrade⁹, Aris Baras¹², Julie Horowitz¹², Manuel A R Ferreira¹², Dylan Sun¹², David E Jones¹³, Steven Flack¹⁴, Ann Spicer¹⁴, Victoria L Mulcahy¹⁴, Jinyoung Byan¹⁵, Younghun Han¹⁵, Richard N Sandford¹⁴, Konstantinos N Lazaridis⁸, Christopher I Amos¹⁵, Gideon M Hirschfield¹⁶, Michael F Seldin¹⁷, Pietro Invernizzi¹⁰, Katherine A Siminovitch¹⁸, Xiong Ma⁶, Minoru Nakamura³, George F Mells¹⁹, Canadian PBC Consortium, Chinese PBC Consortium, Italian PBC Study Group, Japan-PBC-GWAS Consortium, US PBC Consortium, and UK-PBC Consortium

Treatment of primary sclerosing cholangitis

Dig Liver Dis. 2021 May 16;S1590-8658(21)00213-9. doi: 10.1016/j.dld.2021.04.028.Online ahead of print.

Annarosa Floreani¹, Sara De Martin²

Smoking and Liver Disease

Gastroenterol Hepatol (N Y). 2020 Dec;16(12):617-625.

Stephanie M Rutledge¹, Amon Asgharpour

Identification of a Latitude Gradient in the Prevalence of Primary Biliary Cholangitis

Clin Transl Gastroenterol. 2021 May 18;12(5):e00357. doi: 10.14309/ctg.0000000000000357.

Janine French¹, Steve Simpson-Yap^2 3, Ingrid van der Mei³, Justin Ng¹, Peter Angus¹, Paul J Gow¹

10.

Ursodeoxycholic Acid Response Is Associated With Reduced Mortality in Primary Biliary Cholangitis With Compensated Cirrhosis

Am J Gastroenterol. 2021 May 13. doi: 10.14309/ajg.0000000000001280. Online ahead of print.

Binu V John¹, Nidah S Khakoo, Kaley B Schwartz, Gabriella Aitchenson, Cynthia Levy, Bassam Dahman, Yangyang Deng, David S Goldberg, Paul Martin, David E Kaplan, Tamar H Taddei

11.

Detection of anti-mitochondrial 2-oxoacid dehydrogenase complex subunit's antibodies for the diagnosis of primary biliary cholangitis

Clin Immunol. 2021 May 1;108749. doi: 10.1016/j.clim.2021.108749. Online ahead of print.

Elisabet Poyatos¹, Francisco Morandeira², Joan Climent², Virginia Mas², José Castellote³, Jordi Bas²

12.

A Comparison of Prognostic Scores (Mayo, UK-PBC, and GLOBE) in Primary Biliary Cholangitis

Am J Gastroenterol. 2021 May 4. doi: 10.14309/ajg.0000000000001285. Online ahead of print.

Jorn C Goet¹, Carla F Murillo Perez, Maren H Harms, Annarosa Floreani, Nora Cazzagon, Tony Bruns, Florian Prechter, George N Dalekos, Xavier Verhelst, Nikolaos K Gatselis, Keith D Lindor, Willem J Lammers, Aliya Gulamhusein, Anna Reig, Marco Carbone, Frederik Nevens, Gideon M Hirschfield, Adriaan J van der Meer, Henk R van Buuren, Bettina E Hansen, Albert Parés, GLOBAL PBC Study Group

13.

The Management of Cholestatic Liver Diseases: Current Therapies and Emerging New Possibilities

J Clin Med. 2021 Apr 18;10(8):1763. doi: 10.3390/jcm10081763.

Marta Mazzetti^1 2, Giulia Marconi¹, Martina Mancinelli¹, Antonio Benedetti¹, Marco Marzioni¹, Luca Maroni¹

14.

Membranous nephropathy and primary biliary cholangitis: A case report and review of the literature

Clin Nephrol. 2021 Apr 26. doi: 10.5414/CN110363. Online ahead of print.

Jonas Zimmermann, Sigrid Harendza, Mercedes Noriega, Linda Reinhard, Elion Hoxha

15.

Association of bezafibrate with transplant-free survival in patients with primary biliary cholangitis

J Hepatol. 2021 Apr 18;S0168-8278(21)00245-2. doi: 10.1016/j.jhep.2021.04.010.Online ahead of print.

Atsushi Tanaka¹, Junko Hirohara², Toshiaki Nakano², Kosuke Matsumoto³, Olivier Chazouillères⁴, Hajime Takikawa⁵, Bettina E Hansen⁶, Fabrice Carrat⁷, Christophe Corpechot⁸

16.

Short Chain Fatty Acid and Fecal Microbiota Profiles Are Linked to Fibrosis in Primary Biliary Cholangitis

FEMS Microbiol Lett. 2021 Apr 9;fnab038. doi: 10.1093/femsle/fnab038. Online ahead of print.

Craig Lammert¹, Andrea Shin¹, Huiping Xu², Christopher Hemmerich³, Thomas M O'Connell⁴, Naga Chalasani¹

17.

Promyelocytic Leukemia Antigen Expression: a Histological Marker for Primary Biliary Cholangitis Diagnosis?

J Transl Int Med. 2021 Mar 31;9(1):43-51. doi: 10.2478/jtim-2021-0008. eCollection 2021 Mar.

Panagiotis A Papamichalis^1 2, Kalliopi Zachou², Roidoula A Papamichali¹, Maria Ioannou¹, Nikolaos K Gatselis², George N Dalekos², George K Koukoulis¹

18.

Combination of fibrates with obeticholic acid is able to normalise biochemical liver tests in patients with difficult-to-treat primary biliary cholangitis

Aliment Pharmacol Ther. 2021 Mar 25. doi: 10.1111/apt.16336. Online ahead of print.

Pierre-Antoine Soret¹, Laurent Lam¹, Fabrice Carrat¹, Lena Smets², Thomas Berg³, Marco Carbone⁴, Pietro Invernizzi⁴, Vincent Leroy⁵, Palak Trivedi⁶, Nora Cazzagon⁷, Christina Weiler-Normann⁸, Laurent Alric⁹, Isabelle Rosa-Hezode¹⁰, Alexandra Heurgué¹¹, Jean-Paul Cervoni¹², Jérôme Dumortier¹³, Pascal Potier¹⁴, Olivier Roux¹⁵, Christine Silvain¹⁶, Christophe Bureau⁹, Rodolphe Anty¹⁷, Dominique Larrey¹⁸, Cynthia Levy¹⁹, Albert Pares²⁰, Christoph Schramm⁸, Frederik Nevens², Olivier Chazouillères¹, Christophe Corpechot¹

19.

Combination of fibrates with obeticholic acid is able to normalise biochemical liver tests in patients with difficult-to-treat primary biliary cholangitis

Aliment Pharmacol Ther. 2021 Mar 25. doi: 10.1111/apt.16336. Online ahead of print.

20.

Autoimmune Hepatitis-Primary Biliary Cholangitis Overlap Syndrome Triggered by COVID-19

Eur J Case Rep Intern Med. 2021 Feb 4;8(3):002264. doi: 10.12890/2021_002264.eCollection 2021.

Balraj Singh¹, Parminder Kaur², Michael Maroules¹

21.

Safety of fibrates in cholestatic liver diseases

Liver Int. 2021 Mar 9. doi: 10.1111/liv.14871. Online ahead of print.

Andres F Carrion¹, Keith D Lindor², Cynthia Levy³

22.

Accuracy of Transient Elastography in assessing fibrosis at diagnosis in naïve patients with Primary Biliary Cholangitis: a dual cut-off approach

Hepatology. 2021 Mar 16. doi: 10.1002/hep.31810. Online ahead of print.

Laura Cristoferi^1 2 3, Vincenza Calvaruso⁴, Diletta Overi⁵, Mauro Viganò⁶, Cristina Rigamonti⁷, Elisabetta Degasperi⁸, Vincenzo Cardinale⁹, Sara Labanca¹⁰, Nicola Zucchini¹¹, Anna Fichera⁴, Vito Di Marco⁴, Monica Leutner¹², Rosanna Venere¹³, Antonino Picciotto¹⁰, Martina Lucà^1 2, Giacomo Mulinacci^1 2, Andrea Palermo^1 2, Alessio Gerussi^1 2, Daphne D'Amato^1 2, Sarah Elisabeth O'Donnell^1 2, Federica Cerini⁶, Carla De Benedittis⁷, Federica Malinverno^1 2, Vincenzo Ronca^1 2, Clara Mancuso^1 2, Nora Cazzagon¹⁴, Antonio Ciaccio^1 2, Donatella Barisani¹, Marco Marzioni¹⁵, Annarosa Floreani^16 17, Domenico Alvaro⁹, Eugenio Gaudio⁵, Pietro Invernizzi^1 2, Guido Carpino¹⁸, Alessandra Nardi¹⁹, Marco Carbone^1 2, behalf of the Italian PBC Registry

23.

Real-world experience with obeticholic acid in patients with primary biliary cholangitis

JHEP Rep. 2021 Jan 27;3(2):100248. doi: 10.1016/j.jhepr.2021.100248. eCollection 2021 Apr.

Daphne D'Amato¹, Antonio De Vincentis², Federica Malinverno¹, Mauro Viganò³, Domenico Alvaro⁴, Maurizio Pompili⁵, Antonino Picciotto⁶, Valeria Pace Palitti⁷, Maurizio Russello⁸, Silvia Storato⁹, Marie Graciella Pigozzi¹⁰, Vincenza Calvaruso¹¹, Elisabetta De Gasperi¹², Ana Lleo¹³, Antonino Castellaneta¹⁴, Adriano Pellicelli¹⁵, Nora Cazzagon¹⁶, Annarosa Floreani¹⁶, Luigi Muratori¹⁷, Stefano Fagiuoli¹⁸, Grazia Anna Niro¹⁹, Valentina Feletti²⁰, Raffaele Cozzolongo²¹, Natalia Terreni²², Marco Marzioni²³, Rinaldo Pellicano²⁴, Pietro Pozzoni²⁵, Leonardo Baiocchi²⁶, Luchino Chessa²⁷, Floriano Rosina²⁸, Gaetano Bertino²⁹, Maria Vinci³⁰, Anna Morgando²⁴, Ester Vanni²⁴, Gaetano Scifo³¹, Rodolfo Sacco³², Maria D'Antò³³, Valentina Bellia³⁴, Roberto Boldizzoni³⁵, Silvia Casella³⁶, Barbara Omazzi³⁷, Guido Poggi³⁸, Laura Cristoferi¹, Alessio Gerussi¹, Vincenzo Ronca¹, Rosanna Venere⁴, Francesca Ponziani⁵, Maria Cannavò⁸, Alessandro Mussetto²⁰, Rosanna Fontana¹⁹, Francesco Losito²¹, Evelise Frazzetto²⁹, Marco Distefano³¹, Francesca Colapietro¹³, Sara Labanca⁶, Giulia Marconi²³, Giuseppe Grassi²⁶, Giovanni Galati², Sarah Elizabeth O'Donnell¹, Clara Mancuso¹, Giacomo Mulinacci¹, Andrea Palermo¹, Ernesto Claar³⁹, Antonio Izzi⁴⁰, Antonio Picardi², Pietro Invernizzi¹, Marco Carbone¹, Umberto Vespasiani-Gentilucci², Italian PBC Registry and the Club Epatologi Ospedalieri (CLEO)/Associazione Italiana Gastroenterologi ed Endoscopisti Digestivi Ospedalieri (AIGO) PBC Study Group

24.

Home-based exercise in patients with refractory fatigue associated with primary biliary cholangitis: a protocol for the EXerCise Intervention in cholesTatic LivEr Disease (EXCITED) feasibility trial

BMJ Open Gastroenterol. 2021 Mar;8(1):e000579. doi: 10.1136/bmjgast-2020-000579.

Alice Freer^1 2, Felicity Williams^1 3, Simon Durman⁴, Jennifer Hayden², Palak J Trivedi^# 5 2 6, Matthew J Armstrong^# 2

25.

X chromosome contribution to the genetic architecture of primary biliary cholangitis

Gastroenterology. 2021 Mar 3;S0016-5085(21)00466-2. doi: 10.1053/j.gastro.2021.02.061.Online ahead of print.

Rosanna Asselta¹, Elvezia Maria Paraboschi¹, Alessio Gerussi², Heather J Cordell³, George F Mells⁴, Richard N Sandford⁴, David E Jones⁵, Minoru Nakamura⁶, Kazuko Ueno⁷, Yuki Hitomi⁸, Minae Kawashima⁸, Nao Nishida⁸, Katsushi Tokunaga⁹, Masao Nagasaki¹⁰, Atsushi Tanaka¹¹, Ruqi Tang¹², Zhiqiang Li¹³, Yongyong Shi¹³, Xiangdong Liu¹⁴, Ma Xiong¹², Gideon Hirschfield¹⁵, Katherine A Siminovitch¹⁶, Canadian-US PBC Consortium; Italian PBC Genetics Study Group; UK-PBC Consortium; Japan PBC-GWAS Consortium; Marco Carbone², Giulia Cardamone¹, Stefano Duga¹, M Eric Gershwin¹⁷, Michael F Seldin¹⁷, Pietro Invernizzi¹⁸

26.

Quality of life in patients with primary biliary cholangitis: A cross-geographical comparison

J Transl Autoimmun. 2021 Jan 6;4:100081. doi: 10.1016/j.jtauto.2021.100081. eCollection 2021.

Lorenzo Montali¹, Andrea Gragnano¹, Massimo Miglioretti¹, Alessandra Frigerio¹, Luca Vecchio¹, Alessio Gerussi^2 3, Laura Cristoferi^2 3, Vincenzo Ronca^2 3, Daphne D'Amato^2 3, Sarah Elizabeth O'Donnell^2 3, Clara Mancuso^2 3, Martina Lucà^2 3, Minami Yagi⁴, Anna Reig⁵, Laura Jopson⁶, Sesé Pilar⁵, Dave Jones⁶, Albert Pares⁵, George Mells⁷, Atsushi Tanaka⁴, Marco Carbone^2 3, Pietro Invernizzi^2 3

27.

Burden of Primary Biliary Cholangitis Among Inpatient Population in the United States

Hepatol Commun. 2019 Jan 28;3(3):356-364. doi: 10.1002/hep4.1314. eCollection 2019 Mar.

Omer Shahab¹, Mehmet Sayiner¹, James Paik², Sean Felix², Pegah Golabi², Zobair M Younossi^1 2

28.

Investigational drugs in early phase development for primary biliary cholangitis

Expert Opin Investig Drugs. 2021 Feb;30(2):131-141. doi: 10.1080/13543784.2021.1857364.Epub 2020 Dec 11.

Eric M Gochanour¹, Kris V Kowdley¹

29.

Measurement of Gamma Glutamyl Transferase to Determine Risk of Liver Transplantation or Death in Patients With Primary Biliary Cholangitis

Clin Gastroenterol Hepatol. 2020 Aug 7;S1542-3565(20)31083-1.doi: 10.1016/j.cgh.2020.08.006. Online ahead of print.

Alessio Gerussi¹, Davide Paolo Bernasconi², Sarah Elisabeth O'Donnell¹, Willem J Lammers³, Henk Van Buuren³, Gideon Hirschfield⁴, Harry Janssen⁴, Christophe Corpechot⁵, Anna Reig⁶, Albert Pares⁶, Pier Maria Battezzati⁷, Massimo Giovanni Zuin⁷, Nora Cazzagon⁸, Annarosa Floreani⁹, Frederik Nevens¹⁰, Nikolaos Gatselis¹¹, George Dalekos¹¹, Marlyn J Mayo¹², Douglas Thorburn¹³, Tony Bruns¹⁴, Andrew L Mason¹⁵, Xavier Verhelst¹⁶, Kris Kowdley¹⁷, Adriaan van der Meer³, Grazia Anna Niro¹⁸, Benedetta Terziroli Beretta-Piccoli¹⁹, Marco Marzioni²⁰, Luca Saverio Belli²¹, Fabio Marra²², Maria Grazia Valsecchi², Keith D Lindor²³, Pietro Invernizzi¹, Bettina E Hansen²⁴, Marco Carbone²⁵, Italian PBC Study Group and the GLOBAL PBC Study Group

30.

Simplified care-pathway selection for nonspecialist practice: the GLOBAL Primary Biliary Cholangitis Study Group Age, Bilirubin, Alkaline phosphatase risk assessment tool

Eur J Gastroenterol Hepatol. 2020 Dec 14. doi: 10.1097/MEG.0000000000002029.Online ahead of print.

Carla F Murillo Perez^1 2, Aliya Gulamhusein¹, Marco Carbone^3 4, Palak J Trivedi⁵, Adriaan J van der Meer², Christophe Corpechot⁶, Pier Maria Battezzati⁷, Willem J Lammers², Nora Cazzagon^4 8, Annarosa Floreani^4 8, Albert Parés⁹, Frederik Nevens¹⁰, Ana Lleo¹¹, Marlyn J Mayo¹², Kris V Kowdley¹³, Cyriel Y Ponsioen¹⁴, George N Dalekos¹⁵, Nikolaos K Gatselis¹⁵, Douglas Thorburn¹⁶, Andrew L Mason¹⁷, Harry Janssen¹, Xavier Verhelst^4 18, Tony Bruns¹⁹, Keith D Lindor²⁰, Olivier Chazouillères⁶, Pietro Invernizzi^3 4, Bettina E Hansen^1 21, Gideon M Hirschfield¹, GLOBAL PBC Study Group

31.

Utility of palliative EUS-guided biliary drainage using lumen-apposing metal stents: a prospective multicenter feasibility study (with video)

Gastrointest Endosc. 2021 Feb 2;S0016-5107(21)00090-0. doi: 10.1016/j.gie.2021.01.029.Online ahead of print.

Suresh Vasan Venkatachalapathy¹, Martin W James¹, Matthew Huggett², Bharat Paranandi², Stephen P Pereira³, Gavin Johnson⁴, Aloysious D Aravinthan⁵, Guruprasad P Aithal⁵

32.

Is UDCA really a post-transplant panacea?

Liver Transpl. 2021 Jan 19. doi: 10.1002/lt.25989. Online ahead of print.

Cynthia Levy¹, Shahnaz Sultan²

33.

Geo-epidemiology and environmental co-variate mapping of primary biliary cholangitis and primary sclerosing cholangitis

JHEP Rep. 2020 Nov 4;3(1):100202. doi: 10.1016/j.jhepr.2020.100202. eCollection 2021 Feb.

Jessica Katharine Dyson^1 2, Alasdair Blain³, Mark David Foster Shirley⁴, Mark Hudson^1 2, Steven Rushton⁴, David Emrys Jeffreys Jones^1 2

34.

A randomized placebo-controlled trial of elafibranor in patients with primary biliary cholangitis and incomplete response to UDCA

J Hepatol. 2021 Jan 20;S0168-8278(21)00022-2. doi: 10.1016/j.jhep.2021.01.013.Online ahead of print.

Jörn M Schattenberg¹, Albert Pares², Kris V Kowdley³, Michael A Heneghan⁴, Stephen Caldwell⁵, Daniel Pratt⁶, Alan Bonder⁷, Gideon M Hirschfield⁸, Cynthia Levy⁹, John Vierling¹⁰, David Jones¹¹, Anne Tailleux¹², Bart Staels¹², Sophie Megnien¹³, Remy Hanf¹³, David Magrez¹³, Pascal Birman¹³, Velimir Luketic¹⁴

35.

Experimental Pharmacological Agents for the Treatment of Primary Biliary Cholangitis

J Exp Pharmacol. 2020 Dec 17;12:643-652. doi: 10.2147/JEP.S267375.eCollection 2020.

Annarosa Floreani^1 2

36.

Obeticholic acid is associated with improvements in AST-to-platelet ratio index and GLOBE score in patients with primary biliary cholangitis

JHEP Rep. 2020 Sep 29;3(1):100191. doi: 10.1016/j.jhepr.2020.100191. eCollection 2021 Feb.

Maren H Harms¹, Gideon M Hirschfield², Annarosa Floreani³, Marlyn J Mayo⁴, Albert Parés⁵, Alexander Liberman⁶, Elizabeth Smoot Malecha⁶, Richard Pencek⁶, Leigh MacConell⁶, Bettina E Hansen^2 7

37.

Primary biliary cholangitis

Lancet. 2020 Dec 12;396(10266):1915-1926. doi: 10.1016/S0140-6736(20)31607-X.

Ana Lleo¹, Giu-Qiang Wang², Merrill Eric Gershwin³, Gideon M Hirschfield⁴

38.

Portal hypertension in primary biliary cholangitis: prevalence, natural history and histological correlates

Eur J Gastroenterol Hepatol. 2020 Dec 14. doi: 10.1097/MEG.0000000000002033.Online ahead of print.

Thomas W Warnes¹, Stephen A Roberts², Alexander Smith¹, Victor M Cope³, Patricia Vales⁴, Najib Y Haboubi⁵, Raymond F McMahon⁶

39.

UDCA Decreases Incidence of Primary Biliary Cholangitis and Biliary Complications after Liver Transplant: A Meta-Analysis

Liver Transpl. 2020 Nov 13. doi: 10.1002/lt.25935. Online ahead of print.

Mark R Pedersen¹, Garrett Greenan², Sumant Arora³, Arvind Murali³, Marlyn J Mayo¹

40.

Primary Sclerosing Cholangitis and Primary Biliary Cirrhosis Overlap Syndrome: A Review

J Clin Transl Hepatol. 2020 Sep 28;8(3):336-346. doi: 10.14218/JCTH.2020.00036.Epub 2020 Aug 24.

Sheena Mago¹, George Y Wu¹

41.

Fibrates for itch (FITCH) in fibrosing cholangiopathies: a double blind, randomized, placebo-controlled trial

Gastroenterology. 2020 Oct 5;S0016-5085(20)35226-4. doi:10.1053/j.gastro.2020.10.001.Online ahead of print.

Elsemieke de Vries¹, Ruth Bolier¹, Jorn Goet², Albert Parés³, Jef Verbeek⁴, Marleen de Vree⁵, Joost Drenth⁶, Karel van Erpecum⁷, Karin van Nieuwkerk⁸, Frans van der Heide⁵, Nahid Mostafavi¹, Jeltje Helder¹, Cyriel Ponsioen¹, Ronald Oude Elferink¹, Henk van Buuren², Ulrich Beuers⁹, Netherlands Association for the Study of the Liver - Cholestasis Working Group

42.

Genome-wide resolution peripheral blood methylome profiling reveals signatures for cholestatic liver disease

Epigenomics. 2020 Aug;12(16):1363-1375. doi: 10.2217/epi-2020-0048. Epub 2020 Sep 11.

Raymond M Moore¹, Zhifu Sun¹, Brian D Juran², Konstantinos N Lazaridis²

43.

A placebo-controlled randomised trial of budesonide for primary biliary cholangitis following an insufficient response to UDCA

J Hepatol. 2020 Sep 17;S0168-8278(20)33623-0. doi: 10.1016/j.jhep.2020.09.011.Online ahead of print.

G M Hirschfield¹, U Beuers², L Kupcinskas³, P Ott⁴, A Bergquist⁵, M Färkkilä⁶, M P Manns⁷, A Parés⁸, U Spengler⁹, M Stiess¹⁰, R Greinwald¹⁰, M Pröls¹⁰, D Wendum¹¹, U Drebber¹², R Poupon¹³

44.

Liver Stiffness Measured by Either Magnetic Resonance or Transient Elastography Is Associated With Liver Fibrosis and Is an Independent Predictor of Outcomes Among Patients With Primary Biliary Cholangitis

J Clin Gastroenterol. 2020 Sep 23. doi: 10.1097/MCG.0000000000001433. Online ahead of print.

Karim T Osman¹, Daniel B Maselli¹, Ilkay S Idilman², Daniel J Rowan³, Jason K Viehman⁴, William S Harmsen⁴, Denise M Harnois⁵, Elizabeth J Carey⁶, Andrea A Gossard¹, Nicholas F LaRusso¹, Keith D Lindor⁶, Sudhakar K Venkatesh², John E Eaton¹

45.

An update on the management of cholestatic liver diseases

Clin Med (Lond). 2020 Sep;20(5):513-516. doi: 10.7861/clinmed.2020-0697.

Gautham Appanna¹, Yiannis Kallis²

46.

Review article: pathophysiology and management of primary biliary cholangitis

Aliment Pharmacol Ther. 2020 Aug 19. doi: 10.1111/apt.16023. Online ahead of print.

Kristel K Leung^1 2, Maya Deeb^1 2, Gideon M Hirschfield^1 2

47.

Prevalence and long-term outcome of sub-clinical primary sclerosing cholangitis in patients with ulcerative colitis

Liver Int. 2020 Aug 25. doi: 10.1111/liv.14645. Online ahead of print.

Emma L Culver¹, Helen K Bungay², Margaret Betts², Colm Forde^2 3, Otto Buchel⁴, Charis Manganis¹, Bryan F Warren⁵, Jr Fraser Cummings^1 6, Satish Keshav¹, Simon P L Travis¹, Roger W Chapman¹

48.

Role of Antinuclear Antibodies in Primary Biliary Cholangitis

Am J Gastroenterol. 2020 Jul 22. doi: 10.14309/ajg.0000000000000765. Online ahead of print.

Cynthia Levy¹, Christopher L Bowlus²

49.

Reevaluating Goals of Therapy in Primary Biliary Cholangitis: Is Good Enough Is Not Good Enough Anymore?

Am J Gastroenterol. 2020 Jul;115(7):1024-1025. doi: 10.14309/ajg.0000000000000693.

Richard J Bower¹, Catherine Frenette²

50.

Cholangiocarcinoma: Diagnosis and Management

Clin Liver Dis. 2020 Aug;24(3):421-436. doi: 10.1016/j.cld.2020.04.005.Epub 2020 May 29.

Adam P Buckholz¹, Robert S Brown Jr²

51.

Gut microbiome in primary sclerosing cholangitis: A review

World J Gastroentero. 2020 Jun 7;26(21):2768-2780.doi: 10.3748/wjg.v26.i21.2768.

Rebecca Little¹, Eytan Wine², Binita M Kamath¹, Anne M Griffiths¹, Amanda Ricciuto³

52.

How Much Liver Tissue Is Required for Sufficient Histological Staging in Patients With Primary Biliary Cholangitis?

Digestion. 2020 Jun 3;1-9. doi: 10.1159/000507392. Online ahead of print.

Marcel Vetter¹, Andreas E Kremer¹, Abbas Agaimy², Lukas Pfeifer¹, Markus F Neurath¹, Jürgen Siebler¹, Steffen Zopf^3 4

53.

Effects of Primary Biliary Cholangitis on Quality of Life and Health Care Costs in the United Kingdom

Clin Gastroenterol Hepatol. 2020 Jun 17;S1542-3565(20)30836-3.doi: 10.1016/j.cgh.2020.06.025. Online ahead of print.

Stephen Rice¹, Viviana Albani², Dimitrios Minos³, Gulnar Fattakhova², George F Mells⁴, Marco Carbone⁴, Steven Flack⁴, Nikoletta Varvaropoulou⁴, Jonathan Badrock⁴, Ann Spicer⁴, Richard N Sandford⁴, Mark D F Shirley⁵, Diarmuid Coughlan², Gideon Hirschfield⁶, Simon D Taylor-Robinson⁷, UK-PBC Consortium; Luke Vale², David E J Jones⁸

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Vinod S Hegade¹, George F Mells², Holly Fisher³, Stuart Kendrick⁴, Julia DiBello⁵, Kim Gilchrist⁵, Graeme J Alexander², Gideon M Hirschfield⁶, Richard N Sandford⁷, David E J Jones⁸, UK-PBC Consortium

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Angela C Cheung¹, Willem J Lammers², Carla F Murillo Perez³, Henk R van Buuren², Aliya Gulamhusein³, Palak J Trivedi⁴, Konstantinos N Lazaridis¹, Cyriel Y Ponsioen⁵, Annarosa Floreani⁶, Gideon M Hirschfield³, Christophe Corpechot⁷, Marlyn J Mayo⁸, Pietro Invernizzi⁹, Pier Maria Battezzati¹⁰, Albert Parés¹¹, Frederik Nevens¹², Douglas Thorburn¹³, Andrew L Mason¹⁴, Marco Carbone⁹, Kris V Kowdley¹⁵, Tony Bruns¹⁶, George N Dalekos¹⁷, Nikolaos K Gatselis¹⁷, Xavier Verhelst¹⁸, Keith D Lindor¹⁹, Ana Lleo⁹, Raoul Poupon⁷, Harry L A Janssen³, Bettina E Hansen²⁰, Global PBC Study Group

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