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*This program has expired. CME credit is no longer available.

Release Date: 12/18/2019
Expiration Date: 12/18/2020

Target Audience:

This enduring activity has been designed to meet the educational needs of hepatologists, gastroenterologists, and other healthcare professionals involved in the care of patients with cirrhosis.

Goal Statement:

The primary goal of this CME symposium is to better understand how to effectively manage and treat patients with HRS and AKI based on current guidelines and the latest clinical evidence.

Educational Objectives:

After completing this program, participants should be better able to:

  • Define the types of HRS and proposed pathophysiology
  • Discuss the ICA criteria for the diagnosis and management of AKI in cirrhosis and apply these criteria in clinical practice
  • Understand therapies for AKI and HRS and apply recommended treatment strategies to clinical practice

Accreditation Statement:

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Purdue University College of Pharmacy and the Chronic Liver Disease Foundation (CLDF). Purdue University College of Pharmacy, an equal access/equal opportunity institution, is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation:

Purdue University College of Pharmacy designates this live activity for a maximum of 1.5 AMA PRA Category 1 Credits ™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Disclosure Statement:

All faculty, staff and reviewers involved in the planning, review or presentation of continuing education activities provided by Purdue University College of Pharmacy are required to disclose to the audience any relevant commercial financial affiliations related to the content of the presentation or enduring material. Full disclosure of all commercial relationships must be made in writing to the audience prior to the activity.

All additional planning committee members, staff and reviewers of CLDF and Purdue University College of Pharmacy have no relationships to disclose.

For more information visit, email, or call 1-888-565-5321.

Accredited by

Provided by

Supported by an educational grant from Mallinckrodt Pharmaceuticals.

Presented for attendees of the 70th AASLD Annual Meeting. This event/function is sponsored by Chronic Liver Disease Foundation (CLDF), and supported by Mallinckrodt Pharmaceuticals. This is not an official function/event of the American Association for the Study of Liver Diseases.

In case you missed our symposium at the AASLD Conference

Our CME webcast is available now!

Hot Topics in Cirrhosis:


Acute Kidney Injury (AKI) and Hepatorenal Syndrome (HRS)




Introduction and Breaking News
Kimberly Brown, MD, FAST, FAASLD, AGAF

Type 1 HRS: A Medical Emergency
Hugo Vargas, MD

Type 2 HRS: A Slippery Slope
Robert S. Brown, Jr., MD, MPH

AKI vs. HRS: What do I do?
R. Todd Frederick, MD

Panel Discussion/Q&A

Closing Remarks

Back to the Agenda

Kimberly A. Brown, MD (Chair)

Professor of Medicine, Wayne State University
Chief, Gastroenterology and Hepatology
Associate Medical Director, Henry Ford Hospital Transplant Institute
Henry Ford Hospital
Detroit, Michigan

Dr. Kimberly A. Brown is the chief of Gastroenterology and Hepatology at Henry Ford Hospital in Detroit. She joined the Henry Ford Medical Group in 1995 as medical director of the Liver Transplant Program and was appointed chief of the Division of Gastroenterology and Hepatology in 2003. In addition, she served as the Program Director for the GI Fellowship Program from 2003 to 2008. In 2016, she was appointed as the associate medical director for the Henry Ford Hospital Transplant Institute.

Dr. Brown received her undergraduate degree from the University of Michigan in 1981. She completed her medical degree at Wayne State University in 1985. Dr. Brown completed both her residency in internal medicine, as well as her fellowship in gastroenterology, at the University of Michigan in 1992 and was named chief medical resident in 1984-85.

Dr. Brown is a member of the American Gastroenterology Association, the American Association for the Study of Liver Disease, the American College of Gastroenterology, and the American Society of Transplantation. She served on the Board of Governors of the Henry Ford Medical Group for nine years, the Henry Ford Hospital and System Network Board, and was past co-chair of the Michigan Chapter of the American Liver Foundation. She was a founding board member for the ABIM Liver Transplantation and Advanced Hepatology Board. She is past treasurer and board member of the American Society of Transplantation and is involved with several committees for both the Society and hospital. She is a past member of the UNOS Liver and Intestines Committee and previously served on the executive board for the Liver and Intestines Community of Practice for the AST. She is past associate editor for CLDF journal. Currently, Dr. Brown is the secretary for the AASLD and serves on multiple committees in that capacity.

As chief of Gastroenterology and Hepatology and past medical director of Liver Transplantation, Dr. Brown sees and manages patients with complex liver disease both before and after liver transplantation. In conjunction with Dr. Abouljoud, she worked to develop the leading liver transplant program in the State of Michigan. As fellowship director, she managed a fellowship program of 16 GI/liver fellows and continues to be involved in structuring and monitoring their education and academic success. Dr. Brown has trained over 110 fellows in advanced hepatology and transplantation. She has published over 70 articles, 110 abstracts, and eight book chapters/reviews and is a very active clinical investigator in viral hepatitis, advanced liver disease, and post liver-transplant management.


HONORARIA RECIPIENT: Gilead, Pfizer, and Merck.

RESEARCH TO INSTITUTION: Allergan, Conatus, Gilead, and Novartis.

Back to the Agenda

R. Todd Frederick, MD

Transplant Hepatologist
Fellowship Director, Transplant Hepatology
California Pacific Medical Center
San Francisco, California

Dr. R. Todd Frederick is a transplant hepatologist with the San Francisco Center for Liver Disease at California Pacific Medical Center. He currently serves as Clinical Director of Hepatology and Fellowship Director for Transplant Hepatology as well as the Chair of the Clinical Protocols Committee for the Division.

Dr. Frederick received his undergraduate degree in Biology from the University of California, Los Angeles and his medical degree from New York Medical College in Valhalla, New York. He completed both his Internal Medicine Residency and his Fellowship in Gastroenterology/Hepatology at the University of California, San Diego. His clinical and research interests include the management of advanced chronic liver disease and liver failure, artificial liver support systems, hepatorenal syndrome, and portal hypertension, among other topics.



CONSULTANT: Mallinckrodt Pharmaceuticals.

Back to the Agenda

Hugo E. Vargas, MD

Professor of Medicine
Director for Research
Mayo Clinic Alix School of Medicine
Phoenix, Arizona

Dr. Vargas is a Mayo Clinic Consultant in the Department of Gastroenterology and Hepatology and the Mayo Clinic Transplantation Center. He is the Medical Director for the Office of Clinical Research – Arizona, and a Professor of Medicine for the Mayo Clinic Alix School of Medicine in Scottsdale Arizona. Dr. Vargas is the Chair of the Clinical Research Subcommittee (CRS), and the Vice Chair of the Arizona Research Operations Management Team (ROMT).

Dr. Vargas has authored or coauthored more than 125 peer-reviewed articles in journals such as Hepatology, Gastroenterology, American Journal of Transplantation, and New England Journal of Medicine. He is a fellow of the American Association for the Study of Liver Diseases, American College of Gastroenterology, American College of Physicians, American Society of Gastrointestinal Endoscopy and American Gastroenterological Association. He was named Investigator of the Year in 2016 for Mayo Clinic Arizona , and co-chaired the AASLD/IDSA HCV group from 2016-18. In 2010, he received the Outstanding Program Director of the Year Award from the Mayo Clinic College of Medicine's Department of Education Administration.



CONSULTANT: Mallinckrodt Pharmaceuticals



Back to the Agenda

Robert S. Brown, Jr., MD, MPH, AGAF

Gladys and Roland Harriman Professor of Medicine
Vice Chair for Mentorship and Academic Development
Clinical Chief, Division of Gastroenterology and Hepatology
Weill Cornell Medicine
New York, New York

Robert S. Brown, Jr., MD, MPH is vice chair of Mentorship and Academic Development and clinical chief of the Division of Gastroenterology and Hepatology in the Department of Medicine, Weill Cornell Medical College, New York, New York. Dr. Brown is the director of the Center for Liver Disease and Transplantation at New York-Presbyterian Hospital in New York.

Dr. Brown received his bachelor's degree from Harvard College, his medical degree from New York University, and his Master of Public Health from the Graduate School of Public Health, University of California in Berkeley. Following the completion of his medical degree, he fulfilled his internship in medicine at Beth Israel Hospital in Boston and his fellowship in gastroenterology and hepatology at the University of California in San Francisco.

Dr. Brown is an internationally known expert in liver disease and liver transplantation. He has co-authored over 170 peer-reviewed articles most dedicated to viral hepatitis and liver transplantation and has extensive research funding in those areas. He is an associate editor for Hepatology and published a book, Common Liver Diseases and Transplantation: An Algorithmic Approach to Work-up and Management. He was awarded the Young Investigator Award from the American Society of Transplant Physicians, the Senior Attending Teacher Award from Columbia University Medical Center, and the American Liver Foundation New York Chapter's Physician of the Year.


HONORARIA RECIPIENT: AbbVie, Dova, Gilead, Intercept, Merck and Shionogi, Inc.

CONSULTANT/RESEARCH SUPPORT: AbbVie, Dova, Gilead, Intercept, Merck and Shionogi, Inc.


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