:: CLDF ::

Towards eradication of HBV: Treatment approaches and status of clinical trials

Curr Opin Pharmacol. 2021 Aug 30;60:232-240. doi: 10.1016/j.coph.2021.07.008.Online ahead of print.

Lisa Sandmann¹, Markus Cornberg²

Hepadnaviral Lymphotropism and Its Relevance to HBV Persistence and Pathogenesis

Front Microbiol. 2021 Aug 6;12:695384. doi: 10.3389/fmicb.2021.695384.eCollection 2021.

Carla S Coffin¹, Patricia M Mulrooney-Cousins², Tomasz I Michalak²

Liver disease symptoms are associated with higher risk of adverse clinical outcomes: A longitudinal study of North American adults with chronic Hepatitis B

GastroHep. 2021 May;3(3):196-208. doi: 10.1002/ygh2.458. Epub 2021 May 5.

Donna M Evon¹, Hsing-Hua S Lin², Robert J Fontana³, Mandana Khalili⁴, Colina Yim⁵, Abdus S Wahed², Jay H Hoofnagle⁶

Treatment Algorithm for Managing Chronic Hepatitis B Virus Infection in the United States: 2021 Update

Clin Gastroenterol Hepatol. 2021 Jul 27;S1542-3565(21)00818-1. doi: 10.1016/j.cgh.2021.07.036.Online ahead of print.

Paul Martin¹, Mindie H Nguyen², Douglas T Dieterich³, Daryl T-Y Lau⁴, Harry L A Janssen⁵, Marion G Peters⁶, Ira Jacobson⁷

Immunologic markers and risk of hepatocellular carcinoma in hepatitis B virus- and hepatitis C virus-infected individuals

Aliment Pharmacol Ther. 2021 Jul 19. doi: 10.1111/apt.16524. Online ahead of print.

Jill Koshiol¹, Ilona Argirion¹, Zhiwei Liu¹, Tram Kim Lam², Thomas R O'Brien¹, Kelly Yu¹, Katherine A McGlynn¹, Jessica L Petrick^1 3, Ligia Pinto⁴, Chien-Jen Chen^5 6, Allan Hildesheim¹, Ruth M Pfeiffer¹, Mei-Hsuan Lee⁷, Hwai-I Yang⁵

The Inflammatory Cytokine Profile Associated with Liver Damage is Broader and Stronger in Chronic Hepatitis B Patients Compared to Acute Hepatitis B Patients

J Infect Dis. 2021 Jul 21;jiab373. doi: 10.1093/infdis/jiab373. Online ahead of print.

Alexandra Johnson Valiente^1 2, Kin Seng Liem^2 3, Kathleen B Schwarz^4 5, Philip Rosenthal⁶, Karen F Murray⁷, Douglas Mogul⁵, Jeffery Teckman⁸, Norberto Rodriguez-Baez⁹, Sarah Jane Schwarzenberg¹⁰, Jordan J Feld^2 11, David K Wong², Lia L Lewis-Ximenez¹², Georg Lauer¹³, Bettina E Hansen^2 14, Simon C Ling^15 16, Harry L A Janssen^2 11, Adam J Gehring^1 2 11

Hepatitis B Virus (HBV) Genotype: A Significant Risk Factor in Determining which Patients with Chronic HBV Infection should Undergo Surveillance for Hepatocellular Carcinoma: The Hepatitis B Alaska (HEP-B-AK) Study

Hepatology. 2021 Jul 22. doi: 10.1002/hep.32065. Online ahead of print.

Brian J McMahon^1 2, Solu Nolen², Mary Snowball¹, Chriss Homan¹, Susan Negus¹, Elena Roik¹, Philip R Spradling³, Dana Bruden²

Hepatitis B vaccine and risk of acute myocardial infarction among individuals with diabetes mellitus

Pharmacoepidemiol Drug Saf. 2021 Jul 10. doi: 10.1002/pds.5327. Online ahead of print.

Katherine Wong¹, Katia Bruxvoort¹, Jeff Slezak¹, Jin-Wen Y Hsu¹, Kristi Reynolds¹, Lina S Sy¹, Steven J Jacobsen¹

Liver failure from delayed hepatitis B reactivation in anti-HBc-positive patient following rituximab for B-cell lymphoma

BMJ Case Rep. 2021 Jul 9;14(7):e243526. doi: 10.1136/bcr-2021-243526.

Branko Borojevic¹, Ayushi Chauhan², Scott Patterson³

10.

Hepatitis B Screening of At-Risk Immigrants Seen at Primary Care Clinics: A Quality Improvement Project

Mayo Clin Proc Innov Qual Outcomes. 2021 May 27;5(3):635-644.doi: 10.1016/j.mayocpiqo.2021.04.002. eCollection 2021 Jun.

Peace N Eneh¹, Mohamed Mady¹, Mikayla A Schmidt¹, Eneyew Tilahun¹, Fatima Hassan¹, Jane W Njeru², Sarah J Crane², Rajeev Chaudhry², Lewis R Roberts¹

11.

Challenges in Phase 4 post-licensure safety studies using real world data in the United States: Hepatitis B vaccine example

Vaccine X. 2021 Jun 11;8:100101. doi: 10.1016/j.jvacx.2021.100101. eCollection 2021 Aug.

Katia Bruxvoort¹, Lina S Sy¹, Bradley K Ackerson¹, Jeff Slezak¹, Lei Qian¹, William Towner¹, Kristi Reynolds¹, Zendi Solano¹, Cheryl M Carlson¹, Steven J Jacobsen¹

12.

A Deep Ravine Rather Than a Shallow Gap: Many More Bridges Needed to Improve Care of Chronic Hepatitis B in the United States

Am J Gastroenterol. 2021 Jun 30. doi: 10.14309/ajg.0000000000001364. Online ahead of print.

Esperance A K Schaefer¹

13.

Estimated prevalence and number of persons with isolated antibody to hepatitis B core antigen and associated occult hepatitis B, United States, 2001-2018

J Infect Dis. 2021 Jul 12;jiab366. doi: 10.1093/infdis/jiab366. Online ahead of print.

Philip R Spradling¹, Jian Xing¹, Aaron M Harris¹, Kathleen N Ly¹

14.

Moving Fast Toward Hepatitis B Virus Elimination

Adv Exp Med Biol. 2021;1322:115-138. doi: 10.1007/978-981-16-0267-2_5.

Leda Bassit^# 1, Suzane Kioko Ono^# 2, Raymond F Schinazi³

15.

Unexpected Hepatitis B Virus Infection After Liver Transplantation - United States, 2014-2019

MMWR Morb Mortal Wkly Rep. 2021 Jul 9;70(27):961-966. doi: 10.15585/mmwr.mm7027a1.

Danae Bixler, Pallavi Annambhotla, Martha P Montgomery, Tonya Mixon-Hayden, Ben Kupronis, Marian G Michaels, Ricardo M La Hoz, Sridhar V Basavaraju, Saleem Kamili, Anne Moorman

16.

Epidemiology and Prevention of Tuberculosis and Chronic Hepatitis B Virus Infection in the United States

J Immigr Minor Health. 2021 Jun 23. doi: 10.1007/s10903-021-01231-6.Online ahead of print.

Amit S Chitnis¹, Ramsey Cheung^2 3, Robert G Gish⁴, Robert J Wong^2 3

17.

Family imaginaries in the disclosure of a blood-borne virus

Sociol Health Illn. 2021 Jun 23. doi: 10.1111/1467-9566.13316. Online ahead of print.

Anthony K J Smith¹, Asha Persson¹, Kerryn Drysdale^1 2, Joanne Bryant¹, Kylie Valentine³, Jack Wallace⁴, Myra Hamilton⁵, Rebecca M Gray¹, Christy E Newman¹

18.

Hepatitis B virus (HBV) viral load, liver and renal function in adults treated with tenofovir disoproxil fumarate (TDF) vs. untreated: a retrospective longitudinal UK cohort study

BMC Infect Dis. 2021 Jun 26;21(1):610. doi: 10.1186/s12879-021-06226-0.

Tingyan Wang^1 2, David A Smith^2 3, Cori Campbell^1 2, Jolynne Mokaya¹, Oliver Freeman^2 4, Hizni Salih^2 4, Anna L McNaughton¹, Sarah Cripps⁵, Kinga A Várnai^2 3, Theresa Noble^2 3, Kerrie Woods^2 3, Jane Collier⁶, Katie Jeffery⁷, Jim Davies^2 8, Eleanor Barnes^# 9 10, Philippa C Matthews^{# 11 12 13}

19.

Hepatitis B cure: How and when

Liver Int. 2021 Jun;41 Suppl 1:24-29.doi: 10.1111/liv.14837.

Geoffrey Dusheiko¹

20.

Comparison of Novel Biomarkers with Conventional HBV Markers among Untreated Adults with Chronic Hepatitis B in North America

Hepatology. 2021 Jun 16. doi: 10.1002/hep.32018. Online ahead of print.

Marc G Ghany¹, Wendy C King², Mauricio Lisker-Melman³, Anna Sf Lok⁴, Norah Terrault⁵, Harry L A Janssen⁶, Mandana Khalili⁷, Raymond T Chung⁸, William M Lee⁹, Daryl T Y Lau¹⁰, Gavin A Cloherty¹¹, Richard K Sterling¹²

21.

Hepatitis B infections among blood donors in England between 2009 and 2018: Is an occult hepatitis B infection a risk for blood safety?

Transfusion. 2021 Jun 11. doi: 10.1111/trf.16543. Online ahead of print.

Heli Harvala^1 2, Claire Reynolds³, Zoë Gibney⁴, Jade Derrick⁵, Samreen Ijaz⁵, Katy L Davison⁴, Su Brailsford^1 3

22.

Hepatitis B and Hepatitis C among Adults on Probation or Parole in the United States: 2015-2018

J Health Care Poor Underserved. 2021;32(2):671-679. doi: 10.1353/hpu.2021.0096.

Greta Kilmer, Elizabeth Hughes

23.

Prevalence of Hepatitis B Virus (HBV) Infection, Vaccine-Induced Immunity, and Susceptibility among At-Risk Populations: U.S. Households, 2013-2018

Hepatology. 2021 Jun 7. doi: 10.1002/hep.31991. Online ahead of print.

Henry Roberts¹, Kathleen N Ly¹, Shaoman Yin¹, Elizabeth Hughes¹, Eyasu Teshale¹, Ruth Jiles¹

24.

Covalently closed circular DNA: the ultimate therapeutic target for curing Hepatitis B virus infections

J Hepatol. 2021 May 26;S0168-8278(21)00348-2. doi: 10.1016/j.jhep.2021.05.013.Online ahead of print.

Maria Guadalupe Martinez¹, Anders Boyd², Emmanuel Combe¹, Barbara Testoni¹, Fabien Zoulim³

25.

Safety and Effectiveness of Tenofovir Alafenamide in Usual Clinical Practice Confirms Results of Clinical Trials: TARGET-HBV

Dig Dis Sci. 2021 May 31. doi: 10.1007/s10620-021-07033-y. Online ahead of print.

David E Bernstein¹, Huy N Trinh², Eugene R Schiff³, Coleman I Smith⁴, Andrea R Mospan⁵, Richard C Zink⁵, Michael W Fried⁵, Anna S Lok⁶