Medstar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC, USA.
Immunobiology and Transplant Science Center, Houston Methodist Hospital, Texas Medical Center, Houston, TX, USA.
Emory Transplant Center, Emory University School of Medicine, Atlanta, GA, USA.
Significant advances in clinical practice as well as basic and translational science were presented at the American Transplant Congress this year. Topics included innovative clinical trials to recent advances in our basic understanding of the scientific underpinnings of transplant immunology. Key areas of interest included the following: clinical trials utilizing hepatitis C virus-positive (HCV+ ) donors for HCV- recipients, the impact of the new allocation policies, normothermic perfusion, novel treatments for desensitization, attempts at precision medicine, advances in xenotransplantation, the role of mitochondria and exosomes in rejection, nanomedicine, and the impact of the microbiota on transplant outcomes. This review highlights some of the most interesting and noteworthy presentations from the meeting.