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Abstract Details
Diagnostic Performance of the ICD-10 Code K76.82 for Hepatic Encephalopathy in Patients With Cirrhosis
Am J Gastroenterol. 2023 Nov 1. doi: 10.14309/ajg.0000000000002560. Online ahead of print.
1Department of Internal Medicine, Corewell Health William Beaumont University Hospital, Royal Oak, Michigan, USA.
2Division of Gastroenterology and Hepatology, Corewell Health William Beaumont University Hospital, Royal Oak, Michigan, USA.
3Oakland University William Beaumont School of Medicine, Rochester, Michigan, USA.
4Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
Abstract
Introduction: Hepatic encephalopathy (HE) is prevalent and is associated with increased morbidity and mortality among patients with cirrhosis. On October 1, 2022, a new, specific International Classification of Diseases-10 code for HE, K76.82, was introduced. We aimed to analyze the diagnostic accuracy of K76.82.
Methods: Diagnostic performance of K76.82 for HE (sensitivity, specificity, positive predictive ratio, and negative predictive ratio) was evaluated in 2 large health systems compared with lactulose, rifaximin, and K72.90.
Results: A total of 2,483 patients were analyzed. The combination term "lactulose or rifaximin" showed the highest sensitivity of >98% while K76.82 demonstrated a specificity of >87% in all cohorts.
Discussion: Although K76.82 is promising, the combination term "lactulose or rifaximin" identified patients with HE more accurately.
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