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Abstract Details
Inpatient Hepatology Consultation: A Practical Approach for Clinicians
Med Clin North Am. 2023 May;107(3):555-565. doi: 10.1016/j.mcna.2023.01.006.Epub 2023 Feb 20.
1Department of Gastroenterology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
2Hepatology and Liver Transplant Unit, Hospital Universitario Austral, Pilar, Provincia de Buenos Aires, Argentina.
3Hepatology and Liver Transplant Unit, Hospital Central de Las Fuerzas Armadas, Montevideo, Uruguay.
4Hepatology and Liver Transplant Unit, Hospital Universitario Austral, Pilar, Provincia de Buenos Aires, Argentina. Electronic address: mmendiza@cas.austral.edu.ar.
Abstract
Cirrhosis is the end-stage of chronic liver disease and constitutes a leading cause of potential years of working life lost, especially in the Americas and Europe. Its natural history is characterized by an asymptomatic phase called compensated cirrhosis, followed by a rapidly progressive phase characterized by liver-related complications termed decompensated cirrhosis. Complications could be related to portal hypertension and/or liver dysfunction, including ascites, portal hypertensive gastrointestinal bleeding, encephalopathy, and jaundice. This review will discuss some of the most important precipitants of hepatic decompensation, including acute variceal bleeding, spontaneous bacterial peritonitis, and hepatic encephalopathy.