CLDF Title
Home | Contact Us | Bookmark
About CLDF Centers of Educational Expertise  
Live CME Meetings Webcasts Slide Library Abstract Library Conference Highlights
Reuters Health Information (2011-07-11): Hepatitis A infection risk in foreign-born adoptees, their contacts


Hepatitis A infection risk in foreign-born adoptees, their contacts

Last Updated: 2011-07-11 14:02:23 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Foreign-born adopted children are often infected with hepatitis-A, and transmission can occur among both direct and secondary contacts even when the child is asymptomatic, a new study has found.

"Parents, families and other close contacts of adoptees from places where hepatitis A is endemic should be aware of the risk of hepatitis A and how it is spread," said Kristin Sweet, an epidemiologist with the Minnesota Department of Health in St. Paul who led the study.

"A key message is that infants may not have symptoms of hepatitis A, but can still spread the disease," she said in an e-mail to Reuters Health

In her state, one of every ten cases of hepatitis A between 2007 and 2009 was linked with internationally adopted children, she and her colleagues reported online July 4 in Pediatrics.

In their review of data on adoptee-associated hepatitis A cases in Minnesota in those years, Sweet's group found 21 who were infected. The median age of infected children was 11 months. Sixteen were adopted from Ethiopia, three from Guatemala, and two from Liberia.

Hepatitis A is endemic in the 20 most common countries of birth for adoptees, the researchers note.

Only two of the 21 hepatitis A cases were found because of symptoms. Twelve others were identified through routine screening of adoptees from endemic areas; five were found after reported hepatitis A cases led to routine follow-up; and the other two were identified by routine screening at a public health clinic.

Altogether there were 170 patients with hepatitis A in Minnesota during the study period, with 10 cases explained by contact with infected adopted children. Eight of the 10 cases had direct contact with an adoptee infected with hepatitis A, and the other two were infected by someone else who had been in contact with an infected adoptee. Only one of the 10 cases had contact with a symptomatic infected adoptee.

Sweet said that the number of infected adoptees was surprising, and that clinicians need to be aware of the risk of hepatitis A in these adoptees. "Children who are found to be positive for total anti-HAV should be tested for IgM anti-HAV, PEP (post-exposure prophylaxis) should be considered for the adoptee's close contacts," she and the researchers conclude.


Pediatrics 2011.

Slide Library
Abstract Library
Slide Library
Abstract Library
Slide Library
Abstract Library
Slide Library
Abstract Library
Slide Library
Abstract Library
Slide Library
Abstract Library
Slide Library
About CLDF
Mission Statement
Board of Trustees
Board of Advisors
CLDF Sponsors & Supporters
Other Resources
Liver News Library
Journal Abstracts
Hep C Link to Care
Centers of
Educational Expertise
Substance Use Disorder
CLDF Follow Us
  The Chronic Liver Disease Foundation is a non-profit organization with content developed specifically for healthcare professionals.
© Copyright 2012-2018 Chronic Liver Disease Foundation. All rights reserved. This site is maintained as an educational resource for US healthcare providers only.
Use of this Web site is governed by the Chronic Liver Disease Foundation terms of use and privacy statement.