CLDF Title
Home | Contact Us | Bookmark
HBV HE HCC HCV
About CLDF Centers of Educational Expertise  
CME Dinner Meetings Webcasts Slide Library Abstract Library Conference Highlights
 
Back  
 
Reuters Health Information (2007-10-02): Diabetes tied to recurrence of HCV-related hepatocellular cancer

Clinical

Diabetes tied to recurrence of HCV-related hepatocellular cancer

Last Updated: 2007-10-02 11:56:50 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Diabetes is a predictor of poor outcome in patients who have hepatocellular carcinoma related to hepatitis C virus infection (HCV), Japanese investigators report in the September issue of the American Journal of Gastroenterology.

As senior investigator Dr. Shuichi Kaneko told Reuters Health, "Diabetes is a risk factor not only for development of hepatocellular carcinoma, but also for recurrence after operation."

Dr. Kaneko and colleagues at Kanazawa University retrospectively studied 90 patients with hepatitis B and/or C who had undergone surgical treatment for hepatocellular carcinoma. Of this group, 30 had diabetes and the remaining 60 were diabetes-free.

In all, 49 patients had recurrence after surgery. Of these, 22 were from the diabetic group (73.3%) and 27 (45.0%) were from the non-diabetic group. Mean time to recurrence was 32.8 months.

The researchers found that there was no significant difference in survival between diabetic patients and non-diabetic patients with hepatitis B-related hepatocellular carcinoma.

However, comparison of diabetic and non-diabetic patients with HCV-related disease showed that survival rates at 3 years and beyond were significantly lower in the diabetic group than among the non-diabetics. Survival rates at 5 years, for example, were 43.8% versus 82.6%, respectively.

Given these findings, concluded Dr. Kaneko, diabetic patients "should be closely followed for this carcinoma."

Am J Gastroenterol 2007;102:1939-1946.

 
 
 
 
                 
 
HBV
Webcasts
Slide Library
Abstract Library
 
HE
CME Dinner Meeting
Webcasts
Slide Library
Abstract Library
 
HCC
Slide Library
Abstract Library
 
 
HCV
Webcasts
Slide Library
Abstract Library
 
CLDF Follow Us
   
 
About CLDF
Mission Statement
Board of Trustees
Board of Advisors
CLDF Supporters
 
Other Resources
Liver News Library
Journal Abstracts
Hep C Link to Care
 
Centers of
Educational Expertise
Regional Map
     
   
  The Chronic Liver Disease Foundation is a non-profit organization with content developed specifically for healthcare professionals.
© Copyright 2012-2014 Chronic Liver Disease Foundation. All rights reserved. This site is maintained as an educational resource for US healthcare providers only.
Use of this Web site is governed by the Chronic Liver Disease Foundation terms of use and privacy statement.