CLDF Title
Home | Contact Us | Bookmark
HBV HE HCC HCV
About CLDF Centers of Educational Expertise  
CME Dinner Meetings Telewebs Webcasts Slide Library Abstract Library Conference Highlights
 
Back  
 
Reuters Health Information (2005-09-01): Long-standing HCV infection usually leads to cirrhosis

Epidemiology

Long-standing HCV infection usually leads to cirrhosis

Last Updated: 2005-09-01 14:05:07 -0400 (Reuters Health)

NEW YORK (Reuters Health) - In a study of adult Asian patients infected with hepatitis C virus (HCV) in childhood, more than 70% went on to develop cirrhosis, according to a report in the September issue of Clinical Gastroenterology and Hepatology.

Previous reports have shown that about 20% of patients who are infected with HCV for 20 years develop cirrhosis. However, the rate of cirrhosis for longer periods of infection was unclear.

To investigate, Dr. Graham R. Foster, from Queen Mary's School of Medicine and Dentistry in London, and colleagues analyzed data from all patients who had detectable HCV-RNA levels and were evaluated at hospitals in northeast London between 1992 and 2003.

The study group included 143 adult Asian patients who were presumably infected with HCV in childhood and 239 Caucasian patients.

Seventy-eight percent of Asian patients between 61 and 80 years of age had cirrhosis, the report indicates. The corresponding rate in the Caucasian group was lower, 25%, but the authors believe that this simply reflects a shorter duration of infection. For a given duration of infection, the severity of fibrosis seen in each ethnic group was similar.

"This study suggests that prolonged infection with HCV leads to cirrhosis" in most patients, Dr. Foster said in a statement. "While previous studies have found differences in the disease progression in various ethnic groups, our findings confirm that fibrosis progression is the same across these groups and leads to development of cirrhosis and liver disease at the same rate in everyone."

Clin Gastroenterol Hepatology 2005;3:910-917.

 
 
 
 
                 
 
HBV
Webcasts
Slide Library
Abstract Library
 
HE
CME Dinner Meeting
Webcasts
Slide Library
Abstract Library
 
HCC
Slide Library
Abstract Library
 
 
HCV
Webcasts
Slide Library
Abstract Library
 
CLDF Follow Us
   
 
About CLDF
Mission Statement
Board of Trustees
Board of Advisors
CLDF Supporters
 
Other Resources
Liver News Library
Journal Abstracts
Hep C Link to Care
 
Centers of
Educational Expertise
Regional Map
     
   
  The Chronic Liver Disease Foundation is a non-profit organization with content developed specifically for healthcare professionals.
© Copyright 2012-2014 Chronic Liver Disease Foundation. All rights reserved. This site is maintained as an educational resource for US healthcare providers only.
Use of this Web site is governed by the Chronic Liver Disease Foundation terms of use and privacy statement.