CLDF Title
Home | Contact Us | Bookmark
About CLDF Centers of Educational Expertise  
Live CME Meetings Webcasts Slide Library Abstract Library Conference Highlights
Reuters Health Information (2004-12-24): Radiofrequency ablation edges ethanol in liver cancer therapy


Radiofrequency ablation edges ethanol in liver cancer therapy

Last Updated: 2004-12-24 2:11:24 -0400 (Reuters Health)

NEW YORK (Reuters Health) - In patients with hepatocellular carcinomas (HCCs) measuring 4 cm or less, radiofrequency ablation (RF) yields better clinical outcomes than ethanol injection, clinicians from Taiwan report in the December issue of Gastroenterology.

Dr. Shi-Ming Lin and colleagues from Chang Gung Memorial Hospital in Taipei compared the clinical outcome of percutaneous RF, conventional percutaneous ethanol injection (PEI), and higher-dose PEI in 157 patients with 186 such HCCs.

At a mean follow-up of 24.3 months, the rate of complete tumor necrosis was higher in the RF group than in the conventional and higher-dose PEI groups (96% versus 88% and 92%). Patients in the RF group also required significantly fewer treatment sessions to achieve complete tumor necrosis.

In addition, the team reports that RF yielded "not only a lower local tumor progression and a higher cancer-free survival but also a higher overall survival rate" compared with ethanol injection.

On multivariate analysis, tumor size, tumor differentiation, and method of treatment were all significantly related to local tumor progression, and cancer-free and overall survival.

Summing up, the investigators note that although RF ablation is a "relatively low-risk procedure," it was associated with a "slightly higher" rate of major complications compared with ethanol injection. However, there were no RF-related deaths.

Gastroenterology 2004;127:1714-1723.


Slide Library
Abstract Library
Slide Library
Abstract Library
Slide Library
Abstract Library
Live CME Meetings
Slide Library
Abstract Library
Slide Library
Abstract Library
CLDF Follow Us
About CLDF
Mission Statement
Board of Trustees
Board of Advisors
CLDF Supporters
Other Resources
Liver News Library
Journal Abstracts
Hep C Link to Care
Centers of
Educational Expertise
Substance Use Disorder
  The Chronic Liver Disease Foundation is a non-profit organization with content developed specifically for healthcare professionals.
© Copyright 2012-2016 Chronic Liver Disease Foundation. All rights reserved. This site is maintained as an educational resource for US healthcare providers only.
Use of this Web site is governed by the Chronic Liver Disease Foundation terms of use and privacy statement.