CLDF Title
Home | Contact Us | Bookmark
HBV HE HCC HCV
About CLDF Centers of Educational Expertise  
Live CME Meetings Telewebs Webcasts Slide Library Abstract Library Conference Highlights
 
Back  
 
Reuters Health Information (2003-11-21): Aventis warns of liver side effects of Arava drug

Professional Development

Aventis warns of liver side effects of Arava drug

Last Updated: 2003-11-21 15:38:37 -0400 (Reuters Health)

PARIS (Reuters) - France's largest pharmaceuticals company Aventis SA has warned doctors that the use of its rheumatoid arthritis drug Arava (leflunomide) could, in rare cases, seriously damage the liver.

The once-a-day drug is available in 70 countries and was launched in the United States in 1998 and in Europe in 1999.

"In postmarketing experience worldwide, rare, serious hepatic injury, including cases with fatal outcome, have been reported during treatment with Arava," Aventis said in a letter to healthcare professionals in October.

The letter is posted on the Web site of the U.S. Food and Drug Administration.

Aventis said it had updated the prescribing information and monitoring recommendations with the new information.

"The overall safety profile and postmarketing experience with Arava otherwise remain consistent with safety and efficacy demonstrated in our extensive clinical-trial program," Aventis said.

 
 
 
 
                 
 
HBV
Webcasts
Slide Library
Abstract Library
 
HE
Live CME Meetings
Webcasts
Slide Library
Abstract Library
 
HCC
Slide Library
Abstract Library
 
 
HCV
Live CME Meetings
Webcasts
Slide Library
Abstract Library
 
CLDF Follow Us
   
 
About CLDF
Mission Statement
Board of Trustees
Board of Advisors
CLDF Supporters
 
Other Resources
Liver News Library
Journal Abstracts
Hep C Link to Care
 
Centers of
Educational Expertise
Regional Map
     
   
  The Chronic Liver Disease Foundation is a non-profit organization with content developed specifically for healthcare professionals.
© Copyright 2012-2014 Chronic Liver Disease Foundation. All rights reserved. This site is maintained as an educational resource for US healthcare providers only.
Use of this Web site is governed by the Chronic Liver Disease Foundation terms of use and privacy statement.