CLDF Title
Home | Contact Us | Bookmark
HBV HE HCC HCV
About CLDF Centers of Educational Expertise  
Live CME Meetings Telewebs Webcasts Slide Library Abstract Library Conference Highlights
 
Back  
 
Reuters Health Information (2003-11-14): TNF-alpha blockers seem safe for arthritis patients with HCV infection

Clinical

TNF-alpha blockers seem safe for arthritis patients with HCV infection

Last Updated: 2003-11-14 11:15:48 -0400 (Reuters Health)

NEW YORK (Reuters Health) - When used to treat rheumatoid arthritis, tumor necrosis factor (TNF)-alpha antagonists seem to have little effect on liver blood tests or virus levels in patients infected with hepatitis C virus (HCV), new research shows.

Although TNF-alpha blockers are an affective treatment for rheumatoid arthritis, there has been concern about their safety in patients with chronic infections, according to the report published in the November issue of the Annals of the Rheumatic Diseases.

To investigate, Dr. M. H. Wener and colleagues, from the University of Washington in Seattle, measured liver enzyme levels and assessed HCV viral load in 24 rheumatoid arthritis patients with HCV who were treated with etanercept or infliximab.

During a median follow-up period of 9 months, no significant changes in HCV viral load were seen with either anti-TNF agent, the researchers note. Similarly, liver test results at follow-up were not significantly different from those at baseline.

"Long term and larger studies are needed to confirm our results, but the short term data are reassuring," the authors conclude.

Ann Rheum Dis 2003;62:1078-1082.

 
 
 
 
                 
 
HBV
Webcasts
Slide Library
Abstract Library
 
HE
Live CME Meetings
Webcasts
Slide Library
Abstract Library
 
HCC
Slide Library
Abstract Library
 
 
HCV
Live CME Meetings
Webcasts
Slide Library
Abstract Library
 
CLDF Follow Us
   
 
About CLDF
Mission Statement
Board of Trustees
Board of Advisors
CLDF Supporters
 
Other Resources
Liver News Library
Journal Abstracts
Hep C Link to Care
 
Centers of
Educational Expertise
Regional Map
     
   
  The Chronic Liver Disease Foundation is a non-profit organization with content developed specifically for healthcare professionals.
© Copyright 2012-2014 Chronic Liver Disease Foundation. All rights reserved. This site is maintained as an educational resource for US healthcare providers only.
Use of this Web site is governed by the Chronic Liver Disease Foundation terms of use and privacy statement.