CLDF Title
Home | Contact Us | Bookmark
HBV HE HCC HCV
About CLDF Centers of Educational Expertise  
CME Dinner Meetings Telewebs Webcasts Slide Library Abstract Library Conference Highlights
 
Back  
 
Reuters Health Information (2003-10-13): Living donor liver transplants offer fewer complications than cadaveric organs

Clinical

Living donor liver transplants offer fewer complications than cadaveric organs

Last Updated: 2003-10-13 17:13:29 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Living donor liver transplantation (LDLT) is associated with a lower rate of serious complications and rejection and may have a slightly higher survival than orthotopic liver transplantation, according to intermediate term morbidity and mortality data from 92 patients who underwent LDLT at the University of Rochester in New York between 2001 and 2002.

The study represents the largest single-center study of LDLT in the U.S., Dr. Parvez S. Mantry told Reuters Health. He presented the results Monday during the 68th Scientific Meeting of the American College of Gastroenterology in Baltimore, Maryland.

"From the donor standpoint, we published data separately showing that it is an extremely safe procedure," Dr. Mantry told Reuters Health.

In the current study, most recipients tolerated the procedure "very well," he said, with 86% not experiencing any significant complications, and the survival rate was "pretty good," with 92% of patients alive at 6 months.

"Although I published just the intermediate term mortality, we are seeing that patients who underwent LDLT even two or three years ago are for the most part doing quite well," Dr. Mantry told Reuters Health.

The biliary and vascular complication rate for the Rochester LDLT cohort (6.7% and 2.2%, respectively) is lower than that reported nationally (22% and 9.8%, respectively), the research team notes in a meeting abstract.

"The only condition where we have to be a little watchful, and again that is evolving, is chronic hepatitis C," Dr. Mantry said. "These patients may have a higher morbidity from LDLT although those data are not yet completely assimilated."

"LDLT, from my perspective, is a very good alternative to cadaveric liver transplantation mainly because the shortage of organs is so great," Dr. Mantry said.

New York State has the largest waiting list in the country but the least number of organs supplied from cadavers so there is a "huge gap between supply and demand," he explained, "which is why we like to bank on living donor liver transplantation."

Dr. Mantry said he believes that LDLT is "certainly going to catch on and will definitely be a large part of liver transplantation in the future."

 
 
 
 
                 
 
HBV
Webcasts
Slide Library
Abstract Library
 
HE
CME Dinner Meeting
Webcasts
Slide Library
Abstract Library
 
HCC
Slide Library
Abstract Library
 
 
HCV
Webcasts
Slide Library
Abstract Library
 
CLDF Follow Us
   
 
About CLDF
Mission Statement
Board of Trustees
Board of Advisors
CLDF Supporters
 
Other Resources
Liver News Library
Journal Abstracts
Hep C Link to Care
 
Centers of
Educational Expertise
Regional Map
     
   
  The Chronic Liver Disease Foundation is a non-profit organization with content developed specifically for healthcare professionals.
© Copyright 2012-2014 Chronic Liver Disease Foundation. All rights reserved. This site is maintained as an educational resource for US healthcare providers only.
Use of this Web site is governed by the Chronic Liver Disease Foundation terms of use and privacy statement.