Source Hepatology and Liver Transplantation, Cedars-Sinai Medical Center, 8635 W 3rd St, Suite 1060, Los Angeles, CA, 90048, USA, Fred.Poordad@cshs.org.

Hepatitis C is a virus affecting millions worldwide and is a major health risk. With the potentially severe adverse event profile of the current backbone of therapy, interferon, there is an impetus to discover interferon free treatment regimens. With the development of new oral direct acting antivirals, interferon free regimens may be available in the next few years. This article discusses some of the preliminary data from interferon free studies.