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Allele-Specific PCR for Determination of IL28B Genotype |
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Cook L, Diem K, Kim W, Scott JD, Jerome KR. J Clin Microbiol. 2012 Oct 10. [Epub ahead of print] |
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Source
Departments of Laboratory Medicine.
Abstract
IL28B genotype is a critical determinant of interferon response in patients infected with hepatitis C virus genotype 1. We describe an allele-specific PCR assay for IL28B genotype. The assay is simple and robust, uses commonly available real-time PCR instrumentation, and is well suited for clinical laboratories offering IL28B genotyping.
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